Zoo

Question 1

Bacillus Anthracis Clin

Answer 1

Atyp pneumonia and Woolsorters disease with mediastinum widening and pleural effusion. Primary is malaise with mild fever, dyspnea, abdominal pain. Secondary are chest edema, mediastinal lymphoadenopathy, pleural effusion, cyanosis, shock, and death.

Question 2

Bacillus Anthracis Char

Answer 2

Gram pos spore forming rod

Question 3

Bacillus Anthracis VF

Answer 3

Poly-D glutamyl capsule (plasmid)

EF, PA, LF toxins (plasmid)

Question 4

Bacillus Anthracis Res

Answer 4

enviro/animal hide, no PvP

Question 5

Bacillus Anthracis Vccn

Answer 5

Protective Ag = cell free filtrate

Question 6

Bacillus Anthracis Diag

Answer 6

CXR mediastinum widening with PCR

Question 7

Frencensella Tularensis Clin

Answer 7

Tularemia/ atyp pneu with substernal burn, shick, skin ulcer, lymphoadenopathy, granulomas, Rhonchi

Question 8

Frencensella Tularensis RF

Answer 8

Hx outdoor activity

Question 9

Frencensella Tularensis CXR

Answer 9

Patchy ill defined infiltrates

Question 10

Frencensella Tularensis Res

Answer 10

Wild animals

Question 11

Frencensella Tularensis Tx

Answer 11

bacteriocidals

Question 12

Frencensella Tularensis Char

Answer 12

Intracell gram ned bacillus

Question 13

Frencensella Tularensis Lab

Answer 13

Biohazard, serology: paired sera with PCR, culture requires Cysteine

Question 14

Yersinia Pestis Clinical

Answer 14

Pneumonia plague = typ pneumonia and rapid

Bubonic plague = bacteremic, lymphodentrites, PvP aersol, Buboes = inguinal and axial

Question 15

Yersinia Pestis Res

Answer 15

fleas

Question 16

Yersinia Pestis RF

Answer 16

SW USA

Question 17

Yersinia Pestis VF

Answer 17

Coagulase pos, plasminogen pos, Protease gene (degrades C3b/C5a and forms fibrin clots protecting it from opsonization and clearing). Type 3 secretion system: YOPs initiate apoptosis, disrupt actin to destroy host cells ability to phag. Capsule.

Question 18

Bunyviridae: Hantavirus Clin

Answer 18

Hantavirus Pulmonary syndrome with atyp pneumonia and hypertension. Interstitial pulmonary edema.

Question 19

Bunyviridae: Hantavirus Char

Answer 19

enveloped neg sense ss RNA segmented

Question 20

Bunyviridae: Hantavirus Res

Answer 20

Zoo and Rodents (only trans)

Question 21

Bunyviridae: Hantavirus RF

Answer 21

compers and foresters

Question 22

Bunyviridae: Hantavirus Lab

Answer 22

Class 4 labs, elisa (IgM or paired sera IgG); RT-PCR