Upper airway disease

Question 1

UAD

Answer 1

Resp distress. Epiglotitis (H influ), Pertussis (bronchioles and trachea), Croup (obs larynx - parainfluenza), RSV (Bronchiolitis)

Question 2

H Influenza Clin

Answer 2

epiglotitis with thumb sign. Fever and pharyngitis. Stridor

Question 3

H Influenza Char

Answer 3

Gram neg rod, PRP capsule, requires X and V factors

Question 4

H Influenza Diag

Answer 4

Lateral X-ray of neck for thumb sign

Question 5

H Influenza Tx

Answer 5

Hib vccn, rifampin to eliminate carriage

Question 6

Bordetella Pertussis Clin

Answer 6

Whooping cough

Question 7

Bordetella Pertussis Char

Answer 7

gram neg rod

Question 8

Bordetella Pertussis Diag

Answer 8

Bordet-Gengoi or Regan lowe agar, PCR

Question 9

Bordetella Pertussis Vccn

Answer 9

DaPT

Question 10

Bordetella Pertussis Stages

Answer 10

1. Catarrhal (1-2 wks) = cold with fever
2. Paroxysomal (2-4 wks) - destruction of ciliated epi
3. Convalescent - secondary complications = Pneu, seizure, encephalitis

Question 11

Bordetella Pertussis VF

Answer 11

Filamentous Hemaglutinin, Pertactin, Pertussis toxin (PTx/ACT increases cAMP leading to edema, inhibs chemokine receptors, activates islet cells leading to hypoglycemia and increased histamine sensitivity)

Question 12

Parainfluenza Clin

Answer 12

Croup = barking cough

Question 13

Parainfluenza Char

Answer 13

ss neg sense RNA with envelope, H and I peplomers

Question 14

Parainfluenza Diag

Answer 14

Frontal X-ray with steeple sign

Question 15

Parainfluenza Tx

Answer 15

Dexamethasone/ epi to aid resp

Question 16

RSV Clin

Answer 16

Broncholititis with tachypnea, wheeze, Rales, intercostal retract

Question 17

RSV Char

Answer 17

neg sense RNA virus with envelope. F peplomer

Question 18

RSV Diag

Answer 18

IF and PCR

Question 19

RSV Tx

Answer 19

Ribavirin

Question 20

RSV Prev

Answer 20

RSV-Ig (Palivizumab)