Yellow Pages Flashcards
Unilateral hearing loss and ataxia
Acoustic schwannoma
Cerebellopontine angle meningioma
If large enough, can cause hearing loss and V and VII dysfunction
Welling up sensation of doom or fearfulness can be due to what neurological condition
Complex partial seizures
What can cause transient tingling in hands and feet
Hyperventilation
Meniere’s dz
Peripheral Vertigo. Tinnitus, Nausea
>1 episode vertigo. Eventually low freq. hearing loss.
Meniere’s tx
Labyrinthine ablation with gentamicin
What processes can occur subacutely?
Infectious/inflammatory, demyelinating, and autoimmune.
Anti-Yo antibody is
Anti-Purkinje cell.
Associated with small cell lung cancer, gynecologic, and nonHodgkin’s lymphoma.
Where is the Foramen of Monro
Between Lateral and 3rd ventricle
Where is the Cerebral aqueduct (aqueduct of Sylvius)
Between 3rd and 4th ventricle
In the midbrain
Where is the third ventricle
It is sandwiched between both thalami. Above is the Foramen of Monro, below is the cerebral aqueduct
Where is the fourth ventricle
It is ventral to the cerebellum and dorsal to the pons.
Where does the CSF go from the fourth ventricle
It goes into the Subarachnoid space through the Lateral apertures (Luschka) and midline foramen of Magendie.
How to treat NPH?
Shunt
What can meningitis due to Ventricular/CSF system
Scars arachnoid granulations
What is the region of the leg motor fibers in the brain..
The parasagittal region: meningiomas can affect this
GBS CSF
CSF formula is albuminocytologic dissociation
Increased ICP may affect which nerve
Sixth nerve dysfunction (the “nonlocalizing” abducens deficit)
Brainstem astrocytomas, more common in adults or children?
Children
Pediatric tumors are supra or infratentorial
Usually infratentorial, reverse for adults
Transient global aphasia is recurrent and has lasting effects, true or false?
False, it resolves and rarely comes back
Paraneoplastic disorders are reversible?
Nope, generally irreversible damage
Testicular cancer has what paraneopastic disorder?
Anti-Ma
Pump head is what
Hypoxic-ischemic encephalopathy
How to diagnose Creutzfeldt-Jakob
Charactersitic abnormalities in posterior hemispheres on diffusion weighted MRI and presence of 14-3-3 protein in CSF. Disease unlikely if both negative.
Early Alzheimer’s presents with
Paranoia, hoarding behavior, and visuospatial deficits
Treatment of early Alzheimer’s
Can include Quetiapine
Difference between Mild Cognitive Impairment and Dementia
Dementia impairs occupational and social functioning. Both can be amnestic.
MCI prognosis
Can progress to Dementia, stabilize, or get better
Preventing MCI
Challenging the brain like board games or musical instruments
Disease modifying drugs for early AD
Galantamine, donepezil, and rivastigmine
potent enzyme inducer drug
phenytoin and oxcarbazepine
What chemotherapy drugs cause peripheral neuropathies
Docetaxel, paclitaxel, vincristine, platinum
Chemotherapy and cerebellar ataxias
Cytosine arabinoside or 5-FU
Some causes of PRES
preeclampsia, chemotherapy drugs, cyclosporine, and tacrolimus
PRES syndrome findings
HTN, confusion, seizures, and visual changes
Pregnant hypertensive differential
PRES, eclampsia, cerebral venous thrombosis
Treatment for dystonia
Diphenhydramine, why not benztropine?
Erythromycin drug-drug interactions
Can elevate Carbamazepine
AED toxicity
Ataxia, nystagmus, diplopia
Oxcarbazepine bad side effect
AED most associated with hyponatremia
Anticholinergic toxicity sxs
Tachycardia, blurred vision, fever, mental status changes
What does RPLS stand for?
Reversible Posterior Leukoencephalopathy Syndrome
Diabetic sixth nerve palsy cause
Infarct
Pituitary apoplexy is also called
Sheehan’s syndrome
When does Sheehan’s happen
Peripartum
Eyes and chronic steroids
Cataracts
Cluster HA more in men or women
Young men
Cause of INO in old person
Paramedian pontine perforating vessel stroke
Cause of INO in young person
Demyelination
Signs of optic neuritis
Pain on eye movement; central scotoma, normal fundus, poor vision
Papilledema causes what visual field issues
Enlarged blindspot and a centrocecal scotoma
Giant cell arteritis eye complication
Central retinal artery occlusion
Basilar migraine in a child would be what in an adult
Vertebrobasilar TIAs
Posterior Communicating Artery aneurysm leads to
Painful, pupil involving third nerve palsy
What to do for P.comm aneurysm
- CT, 2. LP, 3. Angiography
What happens if an aneurysm is clipped/coiled and deteriorates 3 days later?
Vasospasm. tx with nimodipine
Review herniation syndromes
Uncal Cerebellar Tonsillar Subfalcine Central Upward Locked in
Medical cause of acute angle closure glaucoma
Topiramate
Tunnel vision that doesn’t reveal more as the testing screen is moved further away
Functional, malingering or conversion
Neurofibromatosis type I and eye problem
Optic Nerve glioma
When do you see optic atrophy in optic neuritis
4-6 weeks after the acute event, until then the fundus is likely normal
Most common cause of of Acute Optic neuropathy in patients older than 50
Ischemic Optic Neuropathies
Anterior Ischemic Optic Neuropathy
Can be due to temporal arteritis
Presents with painless vision loss developing over hours to days
Blurred vision and frequently altitudinal field defect.
Generally remains stable.
Risk factors for ION
Congenitally small optic cup, HTN, diabetes
Posterior Ischemic Optic Neuropathy causes
Spinal surgery: irreversible vision loss
Drug causes of ION
Amiodarone, interferon alpha, nasal decongestants, viagra
Cause of a left homonymous hemianopia…
PCA stroke
Why is there Macular sparing if you get a PCA stroke
MCA also supplies macula
How to treat tic douloureux
Carbamazepine
Signs of Temporal Arteritis
ESR elevated; anemia; jaw claudication; diagnose with temporal artery biopsy
Parasagittal lesion that is hyperdense, enhances uniformly is…
Meningioma (extra-axial)
How does a GBM enhance
Heterogeneously and it is intra-axial
What is used for prophylaxis of migraines?
Antihypertensives: Beta blockers, CCBs, ACE inhibitors/Angiotensin Receptor Blocker
Anticonvulsants: Valproate, Topiramate, Gabapentin