Chapter 14: Vascular Disease Flashcards

1
Q

Anterior (carotid) circulation supplies….

A

Cerebral hemispheres except for the medial temporal lobes and a portion of the occipital lobes.

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2
Q

Posterior (vertebro-basilar) circulation supplies…

A

The brainstem, thalami, cerebellum, and the posterior portions of the cerebral hemisphere

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3
Q

Know the anterior and posterior circulations

A

!!!

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4
Q

Percent of ischemic vs. hemorrhagic strokes

A

80% ischemic, 10% subarachnoid and intracerebral hemorrhages each

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5
Q

Different types of ischemic strokes

A

Thrombotic, embolic, and systemic hypoperfusion mechanisms

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6
Q

Thrombotic strokes

A

Large vessels for atherosclerotic

Smaller, penetrating intracranial arteries caused by HTN

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7
Q

Embolisms come mostly from…

A

The heart. Also from the aorta, ICAs, and VAs, and from systemic veins

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8
Q

Systemic Hypoperfusion from…

A

MI or arrhythmia and systemic hypotension from hypovolemia. Think about watershed strokes for this one.

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9
Q

Left Cerebral Hemisphere Strokes signs…

A

Motor: Right hemiparesis (arm,hand,face>leg)
Sensory: Right hemisensory loss
Cognitive: Aphasia

Deep or large lesions: conjugate deviation of the eyes to the left; right hemianopia or hemi-inattention

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10
Q

ICA occlusive disease leads to…

A

Transient monocular visual loss along with the other signs of cerebral hemisphere strokes

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11
Q

Right Cerebral Hemisphere Strokes signs…

A

Motor: Left hemiparesis (arm,hand,face>leg)
Sensory: Left hemisensory loss
Cognitive: Poor drawing, copying, neglect of left visual field

Deep or large lesions: conjugate deviation of the eyes to the right; left hemianopia

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12
Q

Lateral medulla stroke signs

A

Sensory: Ipsilateral facial pain, or reduced pain and temperature sensation on the ipsilateral face, or both;
Loss of pain and temperature in the contralateral limbs and body; Ipsilateral Horner syndrome
Motor: Nystagmus; incoordination of the ipsilateral arm; leaning and veering while sitting or walking with gait ataxia

Deep lesions: Dysphagia and hoarseness

Cause: intracranial VA occlusion

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13
Q

Bilateral pontine base and often medial tegmentum stroke signs

A

Motor: Quadriparesis; unilateral or bilateral conjugate gaze paresis; sometimes internuclear ophthalmoplegia or VIth nerve palsy
Cognitive: Coma if medial tegmentum involved bilaterally

Cause: Basilar artery occlusion, pontine hemorrhage

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14
Q

Cerebellar infarction signs

A

Motor: Gait ataxia (can’t walk); dysarthria; ipsilateral arm dysmetria

Cause: embolism of PICA or SCA or cerebellar hemorrhage

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15
Q

Left PCA territory strokes signs

A

Right hemianopia; right hemisensory symptoms; dysmemory; alexia without agraphia

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16
Q

Right PCA territory stroke signs

A

Left hemianopia; left hemisensory symptoms and left visual neglect

17
Q

PCA territory infarcts are caused mostly by…

A

Embolism to the PCAs arising from the heart, aorta, or VAs

18
Q

Lacunar strokes occur in anterior or posterior circulations…

19
Q

Lacunar Pure motor stroke signs

A

Weakness of arm, face, and leg on one side of the body without sensory, visual, or cognitive or behavioral signs.

20
Q

Lacunar Pure sensory stroke signs

A

Paresthesiae on one side of the body and limbs and face, without motor, visual, or cognitive abnormalities.

21
Q

Lacunar Dysarthria-clumsy hand syndrome signs

A

Slurred speech and clumsiness of one hand

22
Q

Lacunar Ataxic hemiparesis signs

A

Weakness and Ataxia of the limbs on one side of the body

23
Q

Treatment for cardiac embolism stroke, arterial dissection and acute large artery occlusions

A

Heparin and later warfarin

24
Q

Lacunar infarction and nonocclusive atherosclerotic lesions treatment

A

Antiplatelet drugs-aspirin, clopidogrel, a combo of aspirin and modified-release dipyridamole, or cilostazole

25
Other general treatments for strokes
Preventing risk factors: HTN, DM, obesity, HPLD, Smoking
26
Signs of Subarachnoid Hemorrhage
Sudden headache, often vomit, and temporary interruption in behavior
27
SAH cause
Bleed from an aneurysm at the Circle of Willis
28
SAH treatment
Preventing rebleeding and vasocontriction Clipping or coiling the aneurysm CCBs to minimize vasoconstriction and delayed brain ischemia
29
Most common brain vascular malformation
Developmental venous anomalies
30
Developmental venous anomalies (DVAs) are
Anomalous veins usually separated by morphologically normal brain parenchyma
31
How to treat brain vascular malformations
Can use Medical, surgical, interventional obliteration, and radiotherapy