Wound Healing/Tissue Mediators Flashcards by Jamie Pytel | Brainscape

Q

PDGF

A

Secreted by activated platelets and macrophages
Induces vascular remodeling and smooth muscle cell migration
Stimulates fibroblast growth for collagen synthesis

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Q

FGF

A

Stimulates angiogenesis

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Q

EGF

A

Stimulates cell growth via tyrosine kinases (EGFR, as expressed by ERBB2)

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Q

TGF-B

A

Angiogenesis
Fibrosis
Cell cycle arrest

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Q

Metalloproteinases

A

Tissue remodeling

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Q

VEGF

A

Stimulates angiogenesis

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