Oncogenes Flashcards
1
Q
BCR-ABL
A
Tyrosine kinase
CML
ALL
2
Q
BCL2
A
Antiapotptotic molecule
Follicular and undifferentiated lymphomas
3
Q
BRAF
A
Serine/threonine kinase
Melanoma
Non-Hodgkin lymphoma
4
Q
c-kit
A
Cytokine receptor
Gastrointestinal stromal tumor (GIST)
5
Q
c-myc
A
Transcription factor
Burkitt lymphoma
6
Q
HER2/neu (c-erbB2)
A
Tyrosine kinase
Breast carcinoma
Ovarian carcinoma
Gastric carcinoma
7
Q
L-myc
A
Transcription factor
Lung tumor
8
Q
N-myc
A
Transcription factor
Neuroblastoma
9
Q
RAS
A
GTPase
Colon cancer
Lung cancer
Pancreatic cancer
10
Q
RET
A
Tyrosine kinase
MEN2A and 2B
Medullary thyroid cancer