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USMLE- Pathology > Tumor Markers > Flashcards

Tumor Markers Flashcards

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USMLE® Step 1 flashcards
1
Q

Alkaline phosphatase

A

Metastases to bone or liver
Paget disease of bone
Seminoma (placental ALP)

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2
Q

a-fetoprotein

A

Hepatocellular carcinoma
Hepatoblastoma
Yolk sac (endodermal sinus) tumor
Mixed germ cell tumor

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3
Q

B-hCG

A

Hydatidiform moles
Choriocarcinomas
Testicular cancer
Mixed germ cell tumor

(Normally produced by syncytiotrophoblasts of the placenta)

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4
Q

Ca15-3/CA27-29

A

Breast cancer

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5
Q

CA19-9

A

Pancreatic adenocarcinoma

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6
Q

CA125

A

Ovarian cancer

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7
Q

Calcitonin

A

Medullary thyroid carcinom

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8
Q

CEA

A

CarcinoEmbryonic Antigen

Very nonspecific but produced by 70% of colorectal and pancreatic cancer; also produced by gastric, breast, and medullary thyroid cancers

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9
Q

Chromogranin

A

Neuroendocrine tumors/carcinoid

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10
Q

PSA

A

Prostate-specific antigen. Prostate cancer

Can also be elevated in BPH and prostatitis

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USMLE- Pathology (7 decks)

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