Disease Conditions and Associated Neoplasms Flashcards
Acanthosis nigricans
Rare neoplastic indicator of visceral malignancy (more commonly associated with insulin resistance)
Barrett esophagus
Precursor to esophageal adenocarcinoma
Chronic atrophic gastritis, postsurgical gastric remnant
Predispose to gastric adenocarcinoma
Cirrhosis
Predisposes to hepatocellular carcinoma
Ulcerative colitis
Predisposes to colon adenocarcinom
Actinic keratosis
Precursor to squamous cell carcinoma of the skin
Dermato and polymyositis
Predispose to visceral malignancies, particulary genitourinary
Dysplastic nevus
Precursor to malignant melanoma
Multiple seborrheic keratoses
GI, breast, lung, and lymphoid malignancies
Paget disease of the bone
Predisposes to secondary osteosarcoma and fibrosarcoma
Plummer- Vinson syndrome
Predisposes to squamous cell carcinoma of the esophagus
Tuberous sclerosis
Often manifests with multiple hamartomatous (benign) tumors including giant cell astrocytomas, renal angiomyolipomas, cardiac rhabdomyiomas
Tumors may become malignant
Xeroderma pigmentosum
Albinism
Predispose to squamous cell carcinoma, basal cell carcinoma, melanoma
AIDS
Presidposes to aggressive lymphoma (non-Hodgkin) and Kaposi sarcoma
Autoimmune diseases (Hashimotos, SLE)
Predispose to lymphoma