Wound Healing Flashcards
What are the 4 phases of wound healing?
- Inflammation
- Debridement
- Repair (proliferation)
- Remodeling (maturation)
Hemorrhage initiates inflammation by allowing
the ___________ to come into contact with subendothelial
collagen and become activated.
Platelets
Activated platelets secrete products that promote
inflammation and are chemotactic to ______________,
_____________, and cells involved in the repair phase.
Neutrophils, monocytes
What cells are involved in the repair phase of inflammation?
Platelets, monocytes/macrophages, neutrophils
Neutrophils and monocytes/macrophages contribute
to the inflammatory response through the production
of _________________and ________________________________
to prostaglandins and leukotrienes.
Oxygen radicals, metabolism of arachodonic acid
The result of the complex interactions involved in
inflammation___________________________________________________________ from healthy tissues.
is to aid in the isolation of pathogens
and injured tissues
The hallmark signs include ________ ________ _______ ________ __________
pain, heat, redness, and swelling and loss of function.
The ____________________________________ is closely associated with the inflammatory
phase. The cells recruited during inflammation
play a primary role.
removal of devitalized and/or contaminated
tissues
________________ function primarily to kill and remove bacteria from the wound and are _________________ for wound healing.
Neutrophils, Non-essential
_________________ have the primary function of removing foreign or devitalized tissues.
_____________ for wound healing.
Macrophages, Essential
What are the neutrophil actions during debridement?
Production of oxygen radicals
Bactericidal protein and enzymes.
Decrease in number when bacteria are eliminated.
