wound healing

Question 1

stages of wound healing

Answer 1

inflammation, proliferation, remodeling

Question 2

stage 1: inflammation

Answer 2

immediately after injury, 1-5 days, platelets aggregate, vasoconstriction

Question 3

stage 2: proliferation

Answer 3

24-48 hours after injury, 5-21 days, granulation tissue forms and serves as the foundation for scar tissue, granulation secretes growth factors, epithelial cells proliferate to form a new surface and fill the gap

Question 4

stage 3: remodeling

Answer 4

3 weeks after injury, 3-6 months long, scar tissue is structurally refined and reshaped

Question 5

intention

Answer 5

the nature of the wound determines the processes the body uses to heal

Question 6

primary intention

Answer 6

no loss of tissue, clean cut, no scar, regenerated epithelial cells

Question 7

secondary intention

Answer 7

significant loss of tissue, irregular edges, fill wound from the bottom up with beefy red tissue

Question 8

tertiary intention

Answer 8

extensive loss of deep tissue, open for 4-5 days, contaminated

Question 9

dehiscence

Answer 9

when previously closed wound edges open and rupture

Question 10

evisceration

Answer 10

when internal tissues and organs extrude from the open wound

Question 11

keloid formation

Answer 11

increased collagen –> hypertrophic scar

Question 12

contractures

Answer 12

inflexible shrinkage of wound tissue that pulls the edges towards the center of the wound

Question 13

fistula

Answer 13

abnormal connection between tissues and organs

Question 14

adhesions

Answer 14

abnormal bands of scar tissue that can form following invasive procedures