women's health pregnancy and childbirth Flashcards
placenta abrutio
PAINFUL
SUDDEN onset of vaginal bleeding with hard (hypertonic) uterus. > risk with HTN, cocaine. if severe, baby must be delivered
placenta previa
PAINLESS vaginal bleeding
bright red, uterus SOFT
bed rest, no intercourse
magnesium sulfate if cramping
severe preeclampsia
only cure is delivery s/s lated 3rd trimester SEVERE sudden headache edema, weight gain >2lb/week HIGH blood pressure protein in urine
- IF seizure= eclampsia
HELLP syndrome (hemolysis, >liver enzymes, Low platelet)
complication of preeclampsia
RIGHT upper quadrant pain, n/v
?ALT
?AST
protein in urine during pregnancy
abnormal labs and what to do
check midstream urine
protein from 1+ to 4+ is abnormal
if >20 wks, r/o preeclampsia
ir protein present urder 24 hour urine (for protein and creatinine clearance)
which lab > during pregnancy as normal
Alkaline phosphate (ALP) (dt growth of fetal bones)
WBC (up to 16,000) “leukocytosis and neutrophilia” is normal, check s/s
H/H decrease
ESR increase
t3/t4 increase
What is a high neutrophil count?
What is a high neutrophil count?
Neutrophil are the primary white blood cells that respond to a bacterial infection, so the most common cause of neutrophilia is a bacterial infection, especially pyogenic infections. Neutrophils are also increased in any acute inflammation, so will be raised after a heart attack, other infarct or burns.
Leukocytosis
Leukocytosis is defined as a total WBC value of greater than 11,000/microL in adults
normal ANC
norm ANC: 2,500 and 6,000.
The ANC is found by multiplying the WBC count by the percent of neutrophils in the blood
Low AFP results and triple screen
risk for down’s dt maternal age >35yo
if APT Is low order triple screen; AFP, HCG, estriol, inhibit A
screen in jewish for which genetic disorder
tay-sachs (fatal neurological disease, no cure)
screen in whites for which genetic disorder
cystic fibrosis
doubling time
doubling of hcg, only good for 1st trimester ONLY
if values lower than normal, r/o ectopic or inevitable abortion
vaginal cultures during pregnancy and tx
group B; 35-37wks swab introits and rectum
is positive tx with PCN G IV, or clinda/erythro if allergic
which STD to screen in pregnancy
hiv hep b, hep c herpes 1 and 2 gonorrhea/chlamydia syphilis
titers to check during pregnancy
rubella
varicella
most drugs are CATegory B, animal studies show NO risk, no human data available.
cat B drugs
antacids (tums, maalox)
colace
analgesics (acetaminiphin)
antibiotics for pregnancy ok / contraindicated
cat B:
PCN,cephalosporin, macrobid
macrolides- except CLARITHROMCIN (Biaxin)- category C
nitrofurantoin (furandantin, macrobid)- don’t us in g6pd anemia dt hemolysis (anemia, jaundice, dark urine)
category C
septra
nsaids
adverse in animals, no human data
trimethroprim-sulfamethoxazole (bactrim/septra DS)
nsaids (blocks prostaglandins)
what category is ibuprofen/advil during pregnancy
category B (1st and 2nd tri) category D (3d trimester!)- evidence of fetal risk
category D
Acei/arb (ie: capoten/captopril, losartan/hyzaar)
fluroroquinolones (cipro, floxin, levaquin)
* achillis heal rupture/can’t use under 18!
tetracycline- teeth stain (minocycline)
NSAID- premature labor, blocks prostaglandin
SULFa- risk of hyperbilirunemia (neonatal jaundice, kernicterus).
category X
proven fetal risk
accutane
methotrexate- anti metabolite (tx for autoimmune; RA, psoriasis,cancers)
proscar (anti androgen)- BPH, prostate cancer
** misoprostol- drugs for abortions
evista (osteoporosis rx)
LIVE vaccines
LAIV flu mist (flu injection OK)
varicella
MMR
oral polio
- note: after LAIV, reproductive femals should use reliable birth control in the next 4 weeks (MMR) or 3 months (varicella)
teratogens - causes structural abnormalities in fetus
alcohol
aminoglycosides (“mycin”, gentamycin, neomycin, streptomycin)
lithium
chronic hyperglycemia ( poorly controlled DM) can cause neural tube defects/craniofacial defects
health education for pregnancy
folic acid 400mcg (start 3 months before conception)
avoid soft cheese (blue/brie)
no hot tubs
pregnancy weight gain for obese pt
11-20lb
when is fetal heart tones heard
10-12 weeks by doppler ( end of 1st tri)
20 by fetascope