Wk2.2 Neural commutation

Question 1

What is EPSPs and how does it work?

Answer 1

1.Excitatory Postsynaptic Potential

-Glutamate binds to the ion channel allowing Na+ and Ca+ to enter the cell making the cell positive from -70mv to -55mv

-Depolarization

Question 2

What is IPSP and how does it work ?

Answer 2

1.Inhibitory Postsynaptic Potential

-GABA binds to the ion channel gate ,K+ leaves the cell and Cl- enter
- The anion from the K+ is big so it can’t leave so it stays in the cell making the more negative -70mv to -90mv

• Hyperpolarise

Question 3

How can we hit the threshold?

Answer 3

More ESPS than IPSP for depolarisation to have action potential.

Question 4

How does the temporal summation work?

Answer 4

• 2 neutrons one post and pre the post sends glutamate to the postsynaptic and gradually the ESPS hits the TP so more and more glutamate from Pre is sending it to Post synaptic

Question 5

How does spatial summation work?

Answer 5

• Three or more presynaptic neurons send GABA to the one post synaptic neuron which rapidly leads to the EPSP hitting the TP from the RMP.

Question 6

What does EPSP do and how does it not reach tp sometimes?

Answer 6

-Increases voltage from negative to more positive from RMP -70mv to -55mv

• The EPSP may not reach the TP due to the IPSP which leads to the voltage decrease and sometimes going lower than the RMP -70mv to -90mv