wk 2 TB ppt/1 Flashcards
TB - how long taking four drugs
2 months
HIV patients should take INH for how long
9 months
TB is caused by
mycobacterium TB - acid fast bacilli
s/e of INH
4
- peripheral neuritis
- hepatotoxicity
- arthralgias
- optic neuritis
TB - cough
dry cough
TB rank
2nd most common cause of death from infectious disease
TB - if cellular immune system is activated
2
- tissue granuloma forms
2. bacteria is contained, preventing replication and spread
vaccine to prevent TB
bacille calmette guerin BCG (not rec in the US)
what is the gold std for drug therapy success
witness drug adherence
does QFT replace the three negative sputum tests
no
TB drugs - 4 drugs used in initial phase for max effectiveness
- isoniazid INH
- rifampin
- pyrazinamide
- ethambutol
tx while you’re waiting for sputum
broad spectrum antibiotics after blood culture is obtained
TB pleural effusion is caused by
bacteria in pleural space; inflammatory reaction with plural exudates of protein rich fluid
TB s/s in early stages
usually free of s/s
TB clinical manifestations
7
- low grade fever
- weight loss
- anorexia
- night sweats
- fatigue
- malaise
- cough becomes frequent
TB skin test size
5-15 mm of induration depending on risk and exposure
TB spreads how
lymphatic system
factors that influence TB transmission
3
- length of time of exposure (>8 hours)
- amount of particles expelled
- immune system of person
what is the only way to say that TB is cleared - sputum samples
3 sputum samples on three different occasions that come back clear/negative
TB and INH
take alone for 6-9 months for latent infection
TB complications include
4
- pleural effusion
- empyema
- TB pneumonia
- organ involvement
TB favorable environments for growth
5
- upper lobes
- kidneys
- epiphyses of bone
- cerebral cortex
- adrenal glands
TB dx test - sputum collection
collected on different days, three consecutive sputum samples
TB acute s/s
4
- high fever
- chills
- pleuritic pain
- productive cough
