Anemia ppt/2 Flashcards

1
Q

TRALI

A

sudden development of non-cardiogenic pulmonary edema

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2
Q

results in agglutination of cells, which can obstruct capillaries and block blood flow

A

acute hemolytic reaction

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3
Q

allergic reaction s/s

3

A
  1. facial flushing
  2. hives/rash
  3. scratchy
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4
Q

TRALI stands for

A

transfusion related acute lung injury

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5
Q

recipient is sensitive to plasma proteins of the donor’s blood

A

allergic reaction

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6
Q

blood infusion IV G

A

18 or bigger

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7
Q

fibrinolytic system function

A

breaks down newly formed clots creating fibrin split products, which have anticoag properties and inhibit normal blood clotting

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8
Q

massive blood transfusion reaction is an imbalance of

A

normal blood elements

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9
Q

a blood transfusion reaction most often occurs when

A

in the first 10-15 mins or first 50 cc of blood

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10
Q

transfusion reaction - sepsis

A

bacterial contamination of blood product

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11
Q

acute hemolytic reaction s/s

6

A
  1. chills
  2. fever
  3. increased HR
  4. hypotension
  5. chest pain
  6. lumbar pain
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12
Q

is DIC a disease

A

no

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13
Q

circulatory overload - what increases this risk

A

large quantities over short periods of time

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14
Q

febrile reaction can be prevented by

A

using additional filters to leukocyte deplete the RBCs and platelets or ordering leukocytes poor blood products

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15
Q

blood infusion VSs

A

VSs before infusion

VSs 15 mins after started

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16
Q

can give acetaminophen and diphenhydramine 30 mins prior to infusion to prevent this reaction

A

febrile

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17
Q

leader in transfusion-related deaths

A

TRALI

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18
Q

transfusion reaction - acute hemolytic

A

most commonly caused by ABO incompatible blood

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19
Q

TRALI usually occurs when

A

2-6 hours after transfusion, but may occur up to 72 hours after transfusion

20
Q

febrile infusion - can give what

A

acetaminophen and diphenhydramine 30 mins prior to infusion to prevent this reaction

21
Q

allergic reaction - what may be used to treat a severe reaction
2

A
  1. epinephrine

2. corticosteroids

22
Q

anemia diagnostic tests lab findings

4

A
  1. lot plts and fibrinogen
  2. prolonged clotting times
  3. elevated fibrin split products
  4. D-dimer elevated
23
Q

DIC

A

abnormal response of the normal clotting cascade stimulated by a disease process or disorder

24
Q

thrombotic s/s

6

A
  1. cyanosis
  2. ischemic tissue necrosis
  3. tachypnea
  4. pulmonary emboli
  5. paralytic ileus
  6. kidney damage
25
DIC causes widespread what
fibrin and platelet deposit in capillaries and arterioles, resulting in thrombosis
26
circulatory overload - pts with what are at risk for this | 2
cardiac or renal disease
27
fibrinolytic system function ultimately does what
clotting factors are depleted and blood is unable to clot
28
usually occurs 2-6 hours after transfusion, but may occur up to 72 hours after transfusion
TRALI
29
sudden development of non-cardiogenic pulmonary edema
TRALI
30
blood infusion - prime tubing with
NS only
31
massive blood transfusion reaction is a complication of
transfusing large quantities of blood products
32
acute hemolytic reaction - hemolysis of RBCs does what
releases hgb that is excreted in the kidneys and may obstruct renal tubules
33
abnormal response of the normal clotting cascade stimulated by a disease process or disorder
DIC
34
blood administration procedure | 9
1. consent signed 2. lab does type and cross 3. IV 18 G or larger 4. VSs prior 5. set up Y type tubing 6. get blood from bank 7. bedside verification 8. start infusion 9. educate
35
most commonly caused by ABO incompatible blood
acute hemolytic reaction
36
DIC - clotting inhibitor mechanisms are
depressed, resulting in activation of the fibrinolytic system
37
pts with cardiac or renal disease are at risk for this transfusion reaction
circulatory overload
38
reaction - prevent with antihistamines
allergic reaction
39
acute hemolytic reaction can cause what to kidneys | 3
1. acute renal failure 2. DIC 3. death
40
febrile reaction is caused by
leukocyte incompatibility
41
febrile reaction s/s | 6
1. headache 2. tachycardia 3. tachypnea 4. fever 5. chills 6. anxiety
42
epinephrine or corticosteroids may be used to treat a severe reaction
allergic reaction
43
delayed transfusion reactions include | 4
1. delayed hemolytic reaction 2. infections i.e. HIV, CMV, HTLV-1, EBV, malaria 3. iron overload 4. hep B or C
44
allergic reaction - give what to prevent
antihistamines
45
acute hemolytic reaction results in
agglutination of cells, which can obstruct capillaries and block blood flow
46
transfusion allergic reaction
recipient is sensitive to plasma proteins of the donor's blood
47
blood infusion reaction caused by leukocyte incompatibility
febrile reaction