When the immune system goes wrong

Question 1

Type I hypersensitivity results in
a. heparin release by neutrophils
b. histamine release by mast cells
c. histamine release by neutrophils
d. thrombin release by neutrophils
e. thrombin release by mast cells

Answer 1

b

Question 2

Omalizumab is
a. a corticosteroid
b. a β2 agonist
c. an anti-histamine
d. a monoclonal antibody to IgE
e. a monoclonal antibody to histamine

Answer 2

d

Question 3

Autoimmune disease is caused by
a. destruction of T cells and B cells
b. a deficiency of cells of the innate immune system c. absence of tolerance to self antigens
d. the presence of self antigen
e. dysfunction of the spleen

Answer 3

c

Question 4

Autoantibodies are usually
a. IgE
b. IgM
c. IgG
d. IgD
e. IgA

Answer 4

c

Question 5

Autoimmune disease can be treated by a. blood transfusion
b. immune suppression
c. anti-histamines
d. desensitization
e. antibiotics

Answer 5

b

Question 6

HIV infection results in destruction of
a. All lymphocytes
b. CD8+ T cells
c. All white blood cells
d. CD4+ T cells
e. All T cells

Answer 6

d

Question 7

Therapeutic use of cytokines can result in
a. immune deficiency
b. autoimmunity
c. cytokine storm
d. infections by unusual organisms
e. severe allergy

Answer 7

b