What to know for Human Digestion Quiz Flashcards

1
Q

Where does protein digestion begin?

A

stomach

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2
Q

What is the role of Hydrochloric acid in the stomach?

A

HCl conditions in the stomach favor some hydrolysis reactions and help to control pathogens in ingested food

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3
Q

Where does chemical digestion occur?

A

The small intestine

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4
Q

Why is fiber important in a human diet?

A

helps “clean out” old/ damaged intestinal cells and unabsorbed materials, it provides bulk to keep materials moving, it absorbs water to keep faeces soft and easy to pass, “works out” the body’s normal microflora, reduces frequency of constipation, lowers risk of colon and rectal cancers, lowers blood cholesterol, regulates blood sugar levels (slows absorption rate of glucose), and decreases hunger (aids in weight management/ prevention of obesity)

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5
Q

Why can cellulose and lignin not be digested?

A

Cellulose and lignin are not digested because humans do NOT possess enzymes (cellulase) or gut bacteria to break them down

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6
Q

What is the rate of material movement positively correlated with?

A

fiber content

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7
Q

What are waste products egested from the body? ( Hint BILE )

A

bile pigments, epithelial cells, lignin, cellulose, human microflora/ bacteria

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8
Q

What is the main role of the large intestine?

A

MAIN FUNCTION: Absorption of water (and minerals/ vitamins/ ions)
Highly folded – maximizes surface area for absorption of water into the blood

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9
Q

What else does the large intestine do?

A

Secretes mucus-
Lubricates passing feces
Movement of undigested/ undigestable food products- Peristalsis
Egestion- (Understand that materials not absorbed are
egested = BELCH)

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10
Q

What is the general function of villi

A

absorb nutrients ( The inside of the small intestine is lined with villi that absorb nutrients from the liquid mixture called chyme produced in the stomach from the food we eat )

villi increase available surface area for material absorption

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11
Q

What do villi increase?

A

Villi increase the surface area of epithelium over which absorption is carried out.

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12
Q

What do villi absorb?

A

Villi absorb monomers formed by digestion as well as mineral ions and vitamins

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13
Q

What is the structure of cells of the epithelium adapted for?

A

the structure of cells of the epithelium of the villi is adapted to the absorption of food

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14
Q

What is the role of the pancreas in digestion?

A

The pancreas secretes enzymes into the lumen of the small intestine

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15
Q

What is the role of the pancreas in digestion?

A

The pancreas regulates the uptake of glucose
* Insulin increases glucose uptake by cells
* Glucagon decreases glucose uptake by cells

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16
Q

What are the digestive enzymes the pancreas secretes?

A

Salivary amylase, pepsin/protease, amylase, lipase, trypsin/ endopeptidase, nuclease

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17
Q

Nervous mechanism

A

The sight and smell of food trigger an immediate response by which gastric juice is secreted by the stomach during pre-ingestion

When food enters the stomach it causes distention, which is detected by stretch receptors in the stomach lining

Signals are sent to the brain, which triggers the release of digestive hormones to achieve sustained gastric stimulation

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18
Q

Hormonal Mechanism

A

Gastrin is secreted into the bloodstream from the gastric pits of the stomach and stimulates the release of stomach acids
If stomach pH drops too low (becomes too acidic), gastrin secretion is inhibited by gut hormones (secretin and somatostatin)
When digested food (chyme) passes into the small intestine, the duodenum also releases digestive hormones:
Secretin and cholecystokinin (CCK) stimulate the pancreas and liver to release digestive juices
Pancreatic juices contain bicarbonate ions which neutralise stomach acids, while the liver produces bile to emulsify fats

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19
Q

What are some of adaptations of villi?

A

Microvilli, rich blood supply, single layer epithelium, lacteals, intestinal glands, membrane proteins

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20
Q

Microvilli

A

Ruffling of epithelial membrane further increases surface area

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21
Q

Rich blood supply

A

Dense capillary network rapidly transports absorbed products

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22
Q

Single layer epithelium

A

Minimises diffusion distance between lumen and blood

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23
Q

Lacteals

A

Absorbs lipids from the intestine into the lymphatic system

24
Q

Intestinal glands

A

Exocrine pits (crypts of Lieberkuhn) release digestive juices

25
Q

Membrane proteins

A

Facilitates transport of digested materials into epithelial cells

26
Q

What are the digestive enzymes?

A

Salivary amylase, protein/ protease, amylase, lipase, trypsin/ endopeptidase, nuclease

27
Q

Where is the site of production for salivary amylase?

A

Salivary glands

28
Q

Where is the site of action for salivary amylase?

A

Mouth/ esophagus

29
Q

What are the substrates of salivary amylase?

A

Starch ( mauls )

30
Q

What is the product of salivary amylase

A

Maltose

31
Q

Where is the site of product for pepsin/ protease?

A

Stomach

32
Q

Where is the site of action for pepsin/ protease?

A

Stomach

33
Q

What is the substrate for pepsin/ protease?

A

Proteins

34
Q

What is the product of pepsin/protease?

A

Peptides

35
Q

Where is the site of production for amylase?

A

Pancrease

36
Q

Where is the site of action for amylase?

A

Lumen of small intestine

37
Q

What is the substrate of amylase?

A

starch

38
Q

What are the products of amylase?

A

maltose

39
Q

Where is the site of production for trypsin/ endopeptidase

A

Pancrease

40
Q

Where is the site of action for Trypsin/ Endopeptidase?

A

lumen of the small intestine

41
Q

What are the substrates of Trypsin/ Endopeptidase?

A

proteins/ peptides

42
Q

What are the products of Trypsin/ Endopeptidase?

A

amino acids

43
Q

Where is the site of production for lipase?

A

pancreas

44
Q

Where is the site of action for lipase?

A

lumen of the small intestine

45
Q

What are the substrates of lipase?

A

trigycerides

46
Q

What are the products of lipase?

A

Monoglycerides/ fatty acids/ glycerol

47
Q

Where is the site of production for nuclease?

A

Pancreas

48
Q

Where is the site of action for nuclease?

A

lumen of small intestine

49
Q

What are the substrates of nuclease?

A

nucleic acids

50
Q

Simple Diffusion

A

Hydrophobic materials (e.g. lipids) are capable of freely
diffusing across the epithelial membrane

51
Q

Facilitated Diffusion

A

Certain monosaccharides, vitamins and some minerals
may be transported by epithelial channel proteins

52
Q

Secondary Active Transport

A

Glucose and amino acids are co-transported across the
epithelial membrane with sodium ions (Na+)

53
Q

Endocytosis

A

Dissolved materials may be rapidly absorbed en masse via the process of pinocytosis (cell ‘drinking’)

54
Q

How are amino acids digested?

A

Facilitated diffusion and active transport

55
Q

Spell the bacteria that causes stomach ulcers

A

Helicobacter pylori

56
Q

Proton Pumps

A

Proton pump inhibitors (PPIs) are drugs that irreversibly bind to the proton pumps and prevent H+ ion secretion

This effectively raises the pH in the stomach to prevent gastric discomfort caused by high acidity (e.g. acid reflux)
Individuals taking PPIs may have increased susceptibility to gastric infections due to the reduction of acid secretion