Weight Loss Medications

Question 0

phocomelia

Answer 0

birth defect where the arms and legs grow much shorter than normal

Question 1

obesity

Answer 1

medical condition in which excess body fat may have an adverse effect on health - may lead to HTN, hyperlipidemia, and type 2 diabetes

Question 2

what is the level for obesity?

Answer 2

BMI of 30 or above

Question 3

phentermine

Answer 3

CIV- anorexiant - sympathomimetic

• ind. for short term weight loss and get the most results in the first 3 weeks
• 8mg tab - TID
• 15, 18.75, 30mg cap - QDaily

Question 4

phentermine MOA

Answer 4

it is a CNS stimulant that increases NE levels in the brain which stimulates the satiety center that makes you feel full

Question 5

Adipex P

Answer 5

phentermine 37.5mg tab CIV

-anorexiant

Question 6

Suprenza

Answer 6

phentermine 15, 30, 37.5mg ODT CIV

-anorexiant

Question 7

diethylpropion

Answer 7

• anorexiant - sympathomimetic
• tolerance is not as much of a problem as with phentermine
• 25mg tab TID
• 75mg ER tab Qdaily

Question 8

orlistat

Answer 8

-lipase inhibitor- does not decrease appetite: lipase enzymes metabolize dietary fat into free FA

Question 9

adverse effects of orlistat

Answer 9

oily spotting
fecal urgency
flatus with discharge

Question 10

psyllium

Answer 10

ingredient contained in bulk-forming laxatives

-can be taken with orlistat to reduce adverse effects

Question 11

Alli

Answer 11

orlistat 60mg cap TID with meals

-OTC

Question 12

Xenical

Answer 12

orlistat 120mg cap TID with meals

-RX

Question 13

lorcaserin

Answer 13

anorexiant - CIV

• serotonin-2 receptor agonist
• ind. for chronic weight management

Question 14

Belviq

Answer 14

lorcaserin 10mg tab BID

-anorexiant

Question 15

Qsymia

Answer 15

phentermine/topiramate ER cap

• anorexiant
• Qdaily for all strengths
• REMS
• causes birth defects*

Question 16

Qsymia dosing regimen

Answer 16

• start on 3.75mg phen/23mg top for 2 weeks
• then go to 7.5/46 for 12 weeks
• re-evaluate patient at this time
• if there is a need to go up go to 11.25/69 for 2 weeks
• then go to 15/92 for 12 weeks
• re-evaluate again

Question 17

What are the titration doses of Qsymia?

Answer 17

3.75/23 and 11.25/69

Question 18

What are the maintenance doses of Qsymia?

Answer 18

7.5/46 and 15/92