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Dispensing F13 Exam 1 > Antiretroviral Agents > Flashcards

Antiretroviral Agents Flashcards

0
Q

Zerit XR

A

stavudine=d4T

-nucleoside RTI

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1
Q

Retrovir

A

zidovudine=AZT

-nucleoside RTI

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2
Q

Epivir

A

lamivudine=3TC

-nucleoside RTI

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3
Q

Tyzeka

A

telbivudine

-nucleoside RTI

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4
Q

Videx EC

A

didanosine=ddI

  • nucleoside RTI
  • take on an EMPTY stomach*
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5
Q

Ziagen

A

abacavir

-nucleoside RTI

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6
Q

Emtriva

A

emtricitabine

-nucleoside RTI

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7
Q

Viramune

A

nevirapine

-non-nucleoside RTI

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8
Q

Rescriptor

A

delavirdine

-non-nucleoside RTI

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9
Q

Sustiva

A

efavirenz

  • non-nucleoside RTI
  • take on an EMPTY stomach
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10
Q

Intelence

A

etravirine

-non-nucleoside RTI

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11
Q

Edurant

A

rilpivirine

-non-nucleoside RTI

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12
Q

Viread

A

tenofovir

-nucleotide RTI

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13
Q

Truvada

A

emtricitabine, tenofovir

  • combination RTI
  • qdaily
  • now approved for prophylaxis of HIV in high-risk adults
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14
Q

Atripla

A

efavirenz, emtricitabine, tenofovir

  • combination RTI
  • take on an EMPTY stomach
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15
Q

Combivir

A

zidovudine, lamivudine

-combination RTI

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16
Q

Epzicom

A

abacavir, lamivudine

-combination RTI

17
Q

Trizivir

A

abacavir, lamivudine, zidovudine

-combination RTI

18
Q

Complera

A

emtricitabine, rilpivirine, tenofovir

-combination RTI

19
Q

Viracept

A

nelfinavir

  • protease inhibitor
  • take WITH food
20
Q

Lexiva

A

fosamprenavir

  • protease inhibitor
  • take WITH food
21
Q

Invirase

A

saquinavir

  • protease inhibitor
  • take WITH food
22
Q

Norvir

A

ritonavir

  • protease inhibitor
  • take WITH food
23
Q

Crixivan

A

indinavir

  • protease inhibitor
  • take on an EMPTY stomach
24
Q

Reyataz

A

atazanavir

  • protease inhibitor
  • take WITH food
25
Q

Aptivus

A

tipranavir

  • protease inhibitor
  • take WITH food and also with ritonavir for ritonavir boosting
26
Q

Prezista

A

darunavir

  • protease inhibitor
  • take WITH food and also with ritonavir for ritonavir boosting
27
Q

Kaletra

A

lopinavir, ritonavir

  • combination protease inhibitor
  • take WITH food
28
Q

Isentress

A

raltegravir

-integrase inhibitor- another enzyme HIV needs to replicate

29
Q

Selzentry

A

maraviroc

-CCR5 antagonist- prevents HIV from entering the T-cell by blocking CCR5 receptors so HIV can’t get inside

30
Q

Fuzeon

A

enfuvirtide

  • fusion inhibitor- prevents HIV from entering the T-cell by altering the virus and preventing it from fusing to the two receptors
  • subQ injection
31
Q

classes of antiretroviral agents (5)

A 
reverse transcriptase inhibitors
protease inhibitors
integrase inhibitors
fusion inhibitors
CCR5 antagonists
32
Q

3 types of RTIs

A

nucleoside RTIs
non-nucleoside RTIs
nucleotide RTIs

33
Q

nucleoside RTIs (7)

A 
Retrovir
Zerit XR
Epivir
Videx EC
Ziagen
Emtriva
Tyzeka
34
Q

non-nucleoside RTIs - 5

A 
Viramune
Rescriptor
Sustiva
Intelence
Edurant
35
Q

RTI action

A

inhibit reverse transcriptase which is an enzyme that HIV needs to replicate; disease progression is slowed if inhibited

36
Q

ind. of antiretroviral agents

A

treat infections caused by retroviruses

37
Q

antiretroviral agent pt. couseling

A

-DON’T SKIP DOSES

38
Q

what is the point of ritonavir boosting?

A

when taken with Aptivus, Prezista, and Kaletra; ritonavir inhibits the enzyme that metabolizes these drugs to increase the level of the drug

39
Q

combination RTIs (6)

A 
Truvada
Atripla
Combivir
Epzicom
Trizivir
Complera
40
Q

protease inhibitors (9)

A 
Viracept
Lexiva
Invirase
Norvir
Crixivan
Reyataz
Aptivus
Prezista
Kaletra
41
Q

HAART

A

Highly Active AntiRetroviral Therapy

  • used for HIV
  • involves taking multiple antiretroviral agents from different classes at the same time

Dispensing F13 Exam 1 (10 decks)

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