Weeks 1-4 quiz questions Flashcards
Pain in the left shoulder of a 55 year old man is a:
- sign
- symptom
- both
- only a physician is able to determine it
- a symptom
NK cells
- kill only B cells in the peripheral blood
- kill cells of the body expressing class 1 MHC
- kill cells of the body not expressing class 1 MHC
- kills only virus infected cells
- kill cells of the body not expressing class 1 MHC
Etiology:
- studies the causes of a given disease
- studies the epidemiology of a given disease
- studies the therapy of a given disease
- studies the evolution of a given disease
- studies the causes of a given disease
TH2 cells
- are the main player of cytotoxic T cell response
- are the main player in asthma pathogenesis
- are the main player of macrophage activation
- are the main player in antigen presentation
- are the main player in asthma pathogenesis
Non-IgE driven asthma is due essentially to
- TH1 cells and eosinophils
- TH2 cells and eosinophils
- Treg cells and eosinophils
- ILC2 cells and eosinophils
- ILC2 cells and eosinophils
During an infection
- IgM are the memory antibodies
- IgM are the antibodies present in the late phases
- IgG are present in early phase
- IgG are the memory antibodies
- IgG are the memory antibodies
The targets of the autoimmune response in MS
- are melatonin, oligodendrocytes and astrocytes
- are melatonin, oligodendrocytes and schwann cells
- are myelin, oligodendrocytes and schwann cells
- are myelin, oligodendrocytes and astrocytes
- are myelin, oligodendrocytes and schwann cells
NK cells
- kill only B cells in the peripheral blood
- kill cells of the body expressing class I MHC
- kill cells of the body not expressing class I MHC
- kill only virus-infected cells
- kill cells of the body not expressing class I MHC
Mitochondria
- are the organelles where regular proteins synthesis occur
- are the organelles where proteins are glycosylated
- are the organelles where protein traffficking is regulated
- are the organelles where ATP is obtained
ARE THE POWERHOUSE OF THE CELL
Cardinal signs of acute inflammation
- heat, redness and swelling
- heat redness and lost function
- heat, redness and pain
- heat, redness, swelling and pain
- heat, redness, swelling and pain
Swelling in acute inflammation is caused mainly by
- a lymphocytic cell infiltrate
- a neutrophil cell infiltrate
- an increased vascular permeability
- an increased blood flow
- an increased vascular permeability
Chemical mediators of inflammatory vascular response
- serotonin, melatonin, histamin, prostaglandins
- serotonin, histamin, prostaglandins, leukotrienes
- serotonin, histamin, melanin, prostaglandins
- serotonin, histamin, prostaglandins, albumin
- serotonin, histamin, prostaglandins, leukotrienes
Fever
- is a systemic effect on inflammation
- is a local effect of inflammation
- is sometimes a local effect of inflammation
- is a negative symptom in all cases
- is a systemic effect on inflammation
Three growth factors controlling tissue repair after inflammation are
- TGFbeta, VEGF, PDGF
- TGFbeta, GH, VEGF
- TGFbeta, VEGF, PlGF
- TGFbeta, PDGF, PlGF
- TGFbeta, VEGF, PDGF
Th17 cells
- are pro-inflammatory
- inhibit inflammation
- inhibit B cell expansion
- kill viruses directly
- are pro-inflammatory
Thymus
- is where B cells develops
- is where antibodies are formed
- is where immature T cells are educated
- is where mature T cells die normally
- is where immature T cells are educated
Among leukocytes in the whole blood
- Lymphocytes are the most abundant
- Monocytes are the most abundant
- Neutrophils are the most abundant
- Eosinophils are the most abundant
- Neutrophils are the most abundant
When a bacterium is engulfed by a neutrophil
- is killed in a peroxisome
- is killed in a phagolysosome
- is killed in centrosomes
- usually is not killed
- is killed in a phagolysosome
B cells
- are able to kill target cells
- produce antibodies
- mature in the lymph nodes
- kill bacteria directly
- produce antibodies
Nucleolus is
- where DNA is packed
- where DNA is transcribed
- where ribosomes are assembled
- where RNA is translated
- where ribosomes are assembled
Antibodies that protect for long time after vaccination are
- of the IgM class
- of the IgE class
- of the IgA class
- of the IgG class
- of the IgG class
NK cells target
- cells expressing HLA class I molecules
- cells expressing HLA class II molecules
- cells not expressing HLA class I molecules
- cells expressing bacterial antigens
- cells not expressing HLA class I molecules
Pathophysiology
- studies treatment for a given disease
- studies diagnosis for a given disease
- studies mechanisms of disease
- studies the normal function of an organ or apparatus
- studies mechanisms of disease
Epidemiology
- studies diseases at the population level
- studies diseases specifically at the individual level
- studies diseases at the population and at the individual level
- is not based on surveillance of large numbers of subjects
- studies diseases at the population level
Acute inflammation is characterized by
- a slow, indolent onset
- a rapid onset with an initial exudation process and a late cell involvement
- a rapid onset with an initial cell involvement and a late exudation process
- an initial monocyte infiltrate
- a rapid onset with an initial exudation process and a late cell involvement

Growth factors involved in tissue repairs are
- Produced by lymphocytes and plasma cells
- Produced by local tissue fibroblasts
- Produced by macrophages distally to the site of injury
- Produced by macrophages and platelets at the site of injury
- Produced by macrophages and platelets at the site of injury
Swelling during acute inflammation is mainly caused by
- a lymphocyte cell infiltrate
- a neutrophil cell infiltrate
- an increase in vascular permeability
- an increase in blood flow
- an increase in vascular permeability
Three cancers linked to chronic inflammation
- liver, brain and lung
- liver, lung and colon
- kidney, brain and colon
- liver, colon and muscle
- liver, lung and colon
Major cause of colon cancer among the following is
- Crohn disease
- ulcerative colitis
- Whipple disease
- irritable bowel syndrome
- ulcerative colitis
Apoptosis
- is synonym of necrosis
- needs protein synthesis
- triggers an inflammatory response
- induces cellular swelling
- needs protein synthesis
Risk Factors for development of liver cancer are?
- Hepatitis A and Alcohol
- Hepatitis B infection
- Hepatitis C infection
- Hepatitis C infection & Alcohol
Hepatitis C infection & Alcohol
Necrosis …
- needs active protein transcription
- is characterised by cellular condensation
- triggered inflammation in surrounding tissue
- requires ATP
triggered inflammation in surrounding tissue
Acute Inflammation is triggered
- mainly by cells
- mainly by vascular permeability
- mainly by viruses
- mainly by bacteria
- mainly by vascular permeability
Which organelle completes phagocytosis?
- Lysosome
- Mitochondria
- Rough Endoplasmic Reticulum
- Golgi Apperatus
- Lysosome