Week6 Flashcards

1
Q

Purpose of the G1/S checkpoint?

A

evaluate cell health

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2
Q

Purpose of G2/M checkpoint?

A

DNA replication check

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3
Q

Purpose of Spindle checkpoint?

A

Ensure chromosomes are correctly attached

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4
Q

What type of protein holds sister chromatids together?

A

cohesion

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5
Q

When are sister chromatids broken apart?

A

Anaphase

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6
Q

What enzyme breaks down the cohesion bond in anaphase?

A

separase

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7
Q

Haploid definition

A

A cell with one set of chromosomes

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8
Q

Diploid definition

A

a cell with two sets of chromosomes

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9
Q

if it’s haploid number is 40, what is its diploid number?

A

80

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10
Q

is a homologous chromosome equivalent to a haploid or a diploid chromosome set?

A

Diploid

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11
Q

What is included in a diploid count?

A

all chromosomes

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12
Q

what do diploids have in common?

A

length, genes, location, same function

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13
Q

where do diploids differ?

A

nucleotide sequence, came from different parents

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14
Q

What happens during interphase S subphase

A

DNA replication

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15
Q

what direction does DNA replication go in?

A

5 to 3

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16
Q

what direction does transcription read in?

A

5 to 3

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17
Q

what direction does RNA transcription occur in?

A

3 to 5

18
Q

What direction does a leading strand replicate?

A

3 to 5

19
Q

what direction does a lagging strand replicate?

A

5 to 3

20
Q

is a leading strand continuous or discontinous?

A

continuous

21
Q

is a lagging strand continuous or dicontinuous

A

discontinuous

22
Q

What does Helicase do at the beginning of DNA replication

A

unwinds the helix and separates strands

23
Q

what does topoisomerase do at the beginning of DNA replication

A

helps maintain stability while the strand is unwound

24
Q

What makes two homologous (same function chromosomes) duplicated?

A

they are connected

25
Q

why are sister chromatids identical

A

Because they are a result of DNA replication (produced from the same chromosome)

26
Q

why are homologous chromosomes not identical?

A

they are from different parent cells

27
Q

What happens to the spindle in prophase?

A

tubulin becomes centralized

28
Q

what is the building block for spindles

A

tubulin

29
Q

what happens in prophase

A

chromosomes spread throughout cell

30
Q

What happens with the spindle during metaphase?

A

attaches chromosomes to spindle

31
Q

what happens during metaphase?

A

chromosomes become aligned in the middle of the cell (metaphase plate)

32
Q

What happens during Anaphase?

A

sis chromatids separate and go to opposite sides (duplicated chromosomes become unduplicated)

33
Q

what happens during telophase?

A

2 new daughter cells form
spindle starts to disintegrate

34
Q

What does the kinetochore microtubule type in a spindle do?

A

directly connect chromosomes to centrosomes

35
Q

what does the interpolar microtubule type in a spindle do?

A

help separate chromosomes & chromatids

36
Q

what does the astral microtubule type in a spindle do?

A

provide support for centrosomes

37
Q

What microtubule does anaphase A involve?

A

kinetochore

38
Q

what microtubule does anaphase b involve

A

interpolar

39
Q

What is transcription?

A

a process that reads a strand of DNA and produces a protein corresponding to that code

40
Q

How much of DNA is read at a time in transcription?

A

section by section, one gene at a time

41
Q

what happens when a gene is read in transcription?

A

it unwinds, is copied, then rewinds