WEEK2 LEC 213

Question 1

develops when the major blood vessels that supply your heart become
damaged or diseased.

Answer 1

Coronary artery disease

Question 2

usually to blame for coronary artery disease.

Answer 2

Cholesterol-containing deposits (plaques) and inflammation

Question 3

The coronary arteries supply - to your heart

Answer 3

blood, oxygen and nutrients

Question 4

most common cause of cardiovascular disease in the United States and
is characterized by an abnormal accumulation of lipid or fatty substances and fibrous tissue in the
vessel wall. These substances block or narrow the vessel, reducing blood flow to the myocardium

Answer 4

Coronary atherosclerosis

Question 5

Non Modifiable
* Positive family history (a first-degree relative with
cardiovascular disease at age 55 years or younger
for males and at age 65 years or younger for
females)
* Age (more than 45 years for men, more than 55
years for women)
* Gender (men develop cardiovascular disease at an
earlier age than do women)
* Race (higher incidence in African Americans than
in Caucasians)

Answer 5

Coronary atherosclerosis

Question 6

Risk Factors
Modifiable
* High blood cholesterol (hyperlipidemia)
* Cigarette smoking, tobacco use
* Elevated blood pressure
* Hyperglycemia (diabetes mellitus)
* Obesity
* Physical inactivity

Answer 6

Coronary atherosclerosis

Question 7

a clinical syndrome characterized by paroxysms of pain or a feeling of pressure in the anterior chest. The cause is insufficient coronary blood flow, resulting in an inadequate supply of
oxygen to meet the myocardial demand. - is usually a result of atherosclerotic heart disease and
is associated with a significant obstruction of a major coronary artery

Answer 7

Angina Pectoris

Question 8

Clinical Manifestations
* Pain varies from a feeling of indigestion to a choking or heavy sensation in the upper chest ranging
from discomfort to agonizing pain. The patient with diabetes mellitus may not experience severe
pain
* The pain is usually retrosternal, deep in the chest behind the upper or middle third of the sternum.
* Discomfort is poorly localized and may radiate to the neck, jaw, shoulders, and inner aspect of the
upper arms (usually the left arm).
* A feeling of weakness or numbness in the arms, wrists, and hands, as well as shortness of breath,
pallor, diaphoresis, dizziness or lightheadedness, and nausea and vomiting, may accompany the
pain. Anxiety may occur with -.
* An important characteristic of - is that it subsides when the precipitating cause is
removed or with nitroglycerin.