Week One (Part Four) Flashcards
Disorders of the Stomach
Gastritis (List):
Acute Gastritis
Chronic Gastritis
Disorders of the Stomach
Gastritis (Description):
Any of a group of conditions in which the stomach lining is inflamed.
Inflammation, irritation, or erosion of the lining of the stomach. It can occur suddenly (acute) or gradually (chronic).
Disorders of the Stomach
Acute Gastritis
Cause (Etiology):
Caused by local irritant
Disorders of the Stomach
Acute Gastritis
Pathological Changes:
Edema and hyperemia to hemorrhagic erosion
Disorders of the Stomach
Acute Gastritis
Progression:
Self-limited, full recovery
Disorders of the Stomach
Chronic Gastritis
Cause (Etiology):
Autoimmune
Alcoholism
Smoker
Chronic use of NSAIDs
Disorders of the Stomach
Chronic Gastritis
Pathological Changes:
Chronic inflammatory process leading to atrophy of the glandular epithelium. May become dysplastic.
Disorders of the Stomach
Chronic Gastritis
Progression
Autoimmune G- gastric mucosa atrophy, pernicious anemia, cancer
Infectious Gastritis- gastric atrophy and intestinal metaplasia or dysplasia
Peptic Ulcer
Disorders of the Stomach
Peptic Ulcer (Description):
A sore that develops on the lining of the esophagus, stomach, or small intestine.
Disorders of the Stomach
Peptic Ulcer (List):
Duodenal- small intestine (duodenum)
Gastric- stomach
Disorders of the Stomach
Peptic Ulcer
Cause (Etiology):
Predominantly due to H. Pylori
Also NSAIDs
Disorders of the Stomach
Peptic Ulcer
Clinical Manifestation:
Pain when the stomach is empty
Disorders of the Stomach
Peptic Ulcer
Progression:
Remission and exacerbation periods
Obstruction
Bleeding (most common)
Perforation (life threatening)
Disorders of the Stomach
Cancer of the Stomach
Risk Factors:
Genetic predisposition
Carcinogenic substance (nitrate, smoked foods)
Atrophic gastritis, polyps
H. pylori
Disorders of the Stomach
Cancer of the Stomach
Mechanism (Pathology):
Location- pyloric, great curvature
Shape- large, irregular margin
