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CSB601 > Week 8 > Flashcards

Week 8 Flashcards

1
Q

What is nociceptive pain?

A

Pain associated with the sensory system

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2
Q

What is neuropathic pain?

A

Pain related to nerves

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3
Q

How do we manage pain through non-pharmacological mechanisms?

A

Distraction, RICE, reassurance, companionship, exercise

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4
Q

How do we manage pain through pharmacological mechanisms?

A

Paracetamol, NSAIDS, muscle relaxants, opioids, antidepressants

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5
Q

What is the mechanism of action for a NSAID?

A

It inhibits the synthesis of prostaglandins but inhibiting cox 1 and cox 2

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6
Q

What patients shouldn’t have NSAIDS?

A

Cardiovascular, asthma, anticoagulants, renal impairment dehydration, GIT, oldies, preggo and people having surgery

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7
Q

What are the three drug classes in triple whammy?

A

Diuretics, ACE inhibitors, and NSAIDS

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8
Q

What is localized osteoarthritis?

A

Involving 1-2 sites

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9
Q

What is generalized osteoarthritis?

A

Involving 3 or more sites

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10
Q

What is osteoarthritis?

A

It is a metabolically active ongoing process of degradation od a joint

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11
Q

What are some symptoms of osteoarthritis?

A

Pain - acute or chronic

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12
Q

Where is osteoarthritis normally first seen?

A

Finger, wrists, knees, hips and big toes

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13
Q

What are some factors increasing the risk of osteoarthritis?

A

Older age, female, overuse of bone,

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14
Q

What are non-pharmacological management techniques for osteoarthritis?

A

Weight reduction, physiotherapy, heat packs, surgery, splints/wraps, and mobility aids

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15
Q

What is the first-line drug for osteoarthritis?

A

Paracetamol given regularly

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16
Q

What is the second-line drug for osteoarthritis?

A

NSAIDs (lowest dose)

17
Q

What is the third-line drug for osteoarthritis?

A

Opioids

18
Q

What is rheumatoid arthritis?

A

It is a degenerative, autoimmune disorder that attacks the joints and associative tissue

19
Q

Where do we see rheumatoid arthritis?

A

Smaller joints like hands and toes

20
Q

What are the risk factors for rheumatoid arthritis?

A

Genetic link, age, females, lifestyle, infection and people who have never given birth

21
Q

What are some symptoms of rheumatoid arthritis?

A

Pain, stiffness, tenderness, and bilateral symptoms

22
Q

What are the non-pharmacological treatments for rheumatoid arthritis?

A

Lifestyle modifications, heat packs, PT/OT appointments and family living aids

23
Q

What are pharmacological treatments for rheumatoid arthritis?

A

Paracetamol, NSAIDs, corticosteroids,

24
Q

How does methotrexate work?

A

It is a folic acid antagonist and inhibits the DNA synthesis

25
Q

What does bDMARD stand for?

A

biological disease-modifying antirheumatic drugs

26
Q

What kind of drug is infliximab?

A

bDMARD

27
Q

What does cyclooxygenase do?

A

Produce prostaglandins

28
Q

What do prostaglandins do?

A

Make you feel pain and inflammation

CSB601 (10 decks)

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