Week 7 Lecture 7 - Medically Unexplained symptoms Flashcards

1
Q

Kroenke & Price (1993) conducted a large community sample of the lifetime prevalence of 26 common symptoms

They asked what the explanation for symptoms was

What did they find?

A
  • 50.5% due to medically condition or injury
  • 16.4% minor or transient symptoms
  • 2.1% due to medication/substance use

31% no medical diagnosis or explanation!!

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2
Q

What are medically unexplained symptoms?

A

Symptoms for which no medical diagnosis or explanation can be found

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3
Q

What are medically unexplained syndromes?

A

When symptoms occur together regularly in clusters to form a recognisable illness, this may be defined as a “syndrome”

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4
Q

A study looked at consecutive referrals to 7 clinics in 2 London hospitals

What was the percentage of cases for which no medical diagnosis or explanation could be found?

A
  • Dental –> M=50, F=33
  • Chest –> M=26, F=53
  • Neurology –> M=55, F=66
  • Gynaecology –> F=66

around a 1/3 to 2/3 of cases referred to secondary care did not receive a diagnosis

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5
Q

What are the different groups of symptoms that are present in MUS?

A
  • gynaecological symptoms e.g. heavy/painful periods
  • neurological symptoms e.g. seizures, dizziness
  • regional pain presentations e.g. atypical chest pain, headaches
  • musculoskeletal symptoms e.g. low back pain
  • widespread pain/fatigue e.g. chronic fatigue, fibromyalgia
  • gastrointestinal symptoms e.g. abdominal pain
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6
Q

True or false?

MUS often tend to persist for a long time

A

True

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7
Q

A Dutch primary care study (n=254) was conducted with patients with unexplained fatigue, abdominal or musculoskeletal complaints

What was found?

A

43% still had unexplained symptoms 1 year later

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8
Q

People with lots of persistent MUS tend to consult the doctor a lot

What are these people called?

A

“frequent attenders”

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9
Q

What is the problem of MUS?

A
  • MUS violate the biomedical model which conflates disease and illness
    (disease > symptoms > diagnosis > intervention > cure)
  • But MUS are symptoms or illness without disease…
  • If (according to the biomedical model) illness is a sign of disease and a person is ill without a disease, what can be going on?
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10
Q

What is the medical/psychiatric response to MUS violating the biomedical model?

A
  • Somatization
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11
Q

What is somatization?

A
  • psychological difficulty through somatic symptoms
  • unaccounted for by pathological findings
  • to attribute them to physical illness
  • seek medical help
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12
Q

What is the difference between somatization and somatization disorder?

A
  • Somatization: “The process by which psychological distress is expressed as physical symptoms.”
  • “Somatization disorder” a diagnostic label for people with multiple medically unexplained symptoms.
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13
Q

Is somatization as a construct satisfactory?

A
  • no
  • Patients hate it as they feel that it delegitimizes their symptoms
  • What does it mean for “psychological distress” to “come out” as bodily symptoms?
  • There is scant evidence that having lots of bodily symptoms is related to denying emotional problems – in fact the opposite is true
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14
Q

What are MUS often accompanied by

A

psychological symptoms or distress

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15
Q

What did a study of co-occurrence of MUS and psychiatric symptoms in large community sample find?

A

More MUS, greater likelihood of anxiety and depression symptoms

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16
Q

Why is “medically unexplained” an unsatisfactory term?

A
  • Diagnosis by exclusion.
  • Continued concern ‘have we missed something?’
  • indicates failure of medical system
  • Patients can feel dismissed
17
Q

Are the symptoms real in MUS?

18
Q

What is an alternative approach to try and explain MUS?

A

Alternative approaches try to explain the experience of symptoms in terms of interacting biological, psychological and (to a lesser extent) social factors, and help people to manage them.

19
Q

What is a symptom?

A
  • Bodily sensations (e.g. Dizziness, pain)
  • Bodily signs (e.g. Raised temperature)

which are attributed to illness

20
Q

How do we perceive bodily sensations?

A
  • by noticing sensations
  • and then attending to sensations
21
Q

How do we interpret bodily sensations (cognitive factors)?

A
  • Context important
  • Beliefs and personal models of illness, illness prototypes
  • May use heuristics – e.g. stress, age
  • Interpretations affected by emotional factors
22
Q

What did a community study find about how emotion interacts with cognition?

A

In the community, emotion is positively correlated with physical symptoms e.g. fatigue

23
Q

In what ways does emotion interact with cognition?

A
  • Fear of being ill – more vigilant to bodily sensations

Physical sensations of anxiety:
- Sweating, shaking, dry throat, dizzy, nausea, stomach cramps, butterflies

Physical sensations of depression:
- Weight/appetite change, sleeplessness, early waking
- Tiredness, aches and pains

24
Q

Is the interaction between emotion and cognition directional?

A

is bidirectional

25
How are MUS managed in clinical practice?
Many doctors don’t know what to do, so they try: - ‘Reassurance’ (effective for approx 24 hours) - Referral to secondary care departments --> 30-70% no physical pathology - Physical investigation e.g. blood tests - Symptomatic treatment e.g. analgesia Surgery: - e.g. proportion of appendectomies have normal histology
26
Qualitative study (N=68). Interviewed patients with persistent MUS about the different explanations they had received from GPs and other health professionals What was found?
Typology: Rejecting: - Denies reality of symptom - Implies imaginary disorder Implications: - Unresolved explanatory conflict - GP is distrusted with future symptoms Colluding: GP sanctions patient’s own explanation Implications: - Questioning GP’s openness and competence Empowering: - Tangible mechanism - Exculpation - Opportunity for self-management Implications: - Legitimises patient’s suffering and removes blame from patient - Allies GP and patient - Allows for discussion of psychological features - Empowering
27
What are the consequences of the current medical approach to MUS?
- Excessive investigation and treatment - Iatrogenesis* – e.g. unnecessary treatment - Heightened awareness of symptoms The lack of an explanation causes distress: - Patient feels disbelieved - ‘heartsink’ patients - Breakdown of therapeutic relationship
28
What does iatrogenesis mean?
harm caused by healthcare
29
What are psychological approaches to managing MUS?
- Based on the idea that beliefs (cognitions), emotions, and behaviour interact with the body to maintain symptoms
30
How can CBT be used to treat patients with MUS?
- Identifies patients’ interpretations of sensations and beliefs about symptoms - Helps patients to develop alternative models - Promotes behavioural changes - Behavioural changes improve symptoms - Symptom improvement feeds back into beliefs
31
Kroenke & Swindle (2000) conducted a systematic review of 31 controlled trials (29 RCT) of CBT for MUS What was found?
12 month improvement compared with treatment as usual (TAU) in: - Physical symptoms - Functional status - Emotional distress
32
What are some issues in engaging MUS patients with psychological therapy?
- Disenchanted with medical care - Suspicious of mental health services - Beliefs that symptoms are caused by disease - Feel symptoms are not believed - It is important to be able to explain the rationale for treatment convincingly - Sheer volume of individuals with MUS and limited capacity of CBT-trained therapists
33
CBT was adapted to primary care (MUS). What was this called?
Reattribution therapy
34
What is reattribution therapy?
Stages of Reattribution Therapy 1. Feeling understood - Explore illness belief, respond to emotional cues 2. Broadening the agenda - Exploration of emotional factors 3. Making the link - e.g. Stress response, muscle tensions 4. Collaborating on a treatment or management approach
35
Morriss & Gask, 2002 compared patients before GPs trained on reattribution therapy with patients after training was completed. What was found?
- Improvements in patient satisfaction and a decrease in patient somatizing beliefs - Patients with trained GPs less likely to still believe that the cause of their symptoms was purely physical But - No benefit of reduction in healthcare use
36
Morriss et al, 2007 replicated Morriss & Gask, 2002 study with 141 MUS patients in a RCT What was found?
Trained GPs had: 1. Improved GP communication behaviour - Feeling understood (p<.001) - Broadening the agenda (p<.001) - Making the link (p<.001) - Negotiating treatment (p<.001) 2. Increased patient satisfaction (p<.05) 3. No increase in consultation length
37
What conclusions have been made about reattribution therapy?
- ‘simplified’ cognitive behavioural intervention (Reattribution) can be delivered by non-psychology trained health professionals in a way that is feasible and acceptable to patients and NHS - But no studies have yet compared the full cost effectiveness compared with CBT. - Unlikely to be as effective as full CBT for some patients with complex presentations