Week 6 part 2

Question 1

Commonest uterine mass?

Answer 1

Fibroids

Question 2

what is siad to have occured to a uterine fibroid if pain is disproportionate e.g. in pregnancy and menopause?

Answer 2

Red degeneration

Question 3

What invesgitations are done for suspected fibroids?

Answer 3

Haemoglobin if heavy bleeding
Ultrasound - smooth echogenic mass
MRI for precise location

Question 4

Fibroid treatment?

Answer 4

Traditionally hysterectomy if family complete

Question 5

Give to examples of functional ovarian cysts related to ovulation?

Answer 5

1. Follicular cyst

2. Luteal cyst

Question 6

What cysts are typically associated with severe dysmenorrhaoea and premenstrual pain, also dyspareunia and often associated with subfertility?

Answer 6

Endometriotic cysts

Question 7

Give an example of a benign cystic teratoma (arising from germ cell, primary ovarian tumour)?

Answer 7

Dermoid cyst

Question 8

What is Meigs syndrome?

Answer 8

Triad of benign ovarian tumour (fibroma) with ascites and pleural effusion

Question 9

What might malignant germ cell tumorus of ovary produce?

Answer 9

HCG or AFP

Question 10

BRACA1 & 2?

Answer 10

Breast and ovarian cancer

Question 11

HNPCC

Answer 11

Lynch syndrome - colorectal cancer, endometrial cancer, ovarian cancer

Question 12

What is protective factor for ovarian cancer?

Answer 12

OCP

Question 13

Ovarain cancer tumour marker?

Answer 13

CA 125 - RAISED in 80% of cancer

Carcino-embryonic antigen CEA

Question 14

What can endometriosis, peritonitis, pregnancy, pancreatitis, ascites all cause a moderate elevation in??

Answer 14

CA-125

Question 15

What ovarian tumours cause a particular rise in carcino embryonic antigen CEA? Mian function of CEA is to exclude mets from GI primary

Answer 15

mUcinous tumours

Question 16

How do you calculate RMI for ovarian cancer?

Answer 16

Menopausal status x serum CA125 x US score

Question 17

What biochemistry test should be requested when investigating ovarian canceR?

Answer 17

Serum albumin

Question 18

ascites/ bloating
pelvic mass/ bladder dysfunction
pleural effusion/shortness of breath

Answer 18

Ovarian cancer

Question 19

Patient with an RMI above what should be referred to hospital?

Answer 19

Above 200

Question 20

FIGO staging of ovarian cancer: confined to 1 or both ovaries

Answer 20

I

Question 21

FIGO staging of ovarian cancer: spread beyond pelkvis within the abdomen?

Answer 21

III

Question 22

FIGO staging of ovarian cancer: Spread to other pelvic organs e.g. uterus, fallopian tube

Answer 22

II

Question 23

FIGO staging of ovarian cancer: spread into other organs e.g. liver, lungs?

Answer 23

iv

Question 24

What should all women with high grade early stage Ia-Ib ovarian cancer ben considered for?

Answer 24

Chemotherapy

Question 25

For advanced disease ovarian cancer what is drug of choice for both single and combnation therapy?

Answer 25

Carboplatin (platinum drug)

Question 26

What are the most common extra-abdominal cancers that cause malignant bowel obstruction?

Answer 26

Breast Melanoma Lung