Week 6 part 2 Flashcards

1
Q

Commonest uterine mass?

A

Fibroids

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2
Q

what is siad to have occured to a uterine fibroid if pain is disproportionate e.g. in pregnancy and menopause?

A

Red degeneration

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3
Q

What invesgitations are done for suspected fibroids?

A

Haemoglobin if heavy bleeding
Ultrasound - smooth echogenic mass
MRI for precise location

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4
Q

Fibroid treatment?

A

Traditionally hysterectomy if family complete

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5
Q

Give to examples of functional ovarian cysts related to ovulation?

A
  1. Follicular cyst

2. Luteal cyst

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6
Q

What cysts are typically associated with severe dysmenorrhaoea and premenstrual pain, also dyspareunia and often associated with subfertility?

A

Endometriotic cysts

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7
Q

Give an example of a benign cystic teratoma (arising from germ cell, primary ovarian tumour)?

A

Dermoid cyst

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8
Q

What is Meigs syndrome?

A

Triad of benign ovarian tumour (fibroma) with ascites and pleural effusion

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9
Q

What might malignant germ cell tumorus of ovary produce?

A

HCG or AFP

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10
Q

BRACA1 & 2?

A

Breast and ovarian cancer

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11
Q

HNPCC

A

Lynch syndrome - colorectal cancer, endometrial cancer, ovarian cancer

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12
Q

What is protective factor for ovarian cancer?

A

OCP

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13
Q

Ovarain cancer tumour marker?

A

CA 125 - RAISED in 80% of cancer

Carcino-embryonic antigen CEA

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14
Q

What can endometriosis, peritonitis, pregnancy, pancreatitis, ascites all cause a moderate elevation in??

A

CA-125

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15
Q

What ovarian tumours cause a particular rise in carcino embryonic antigen CEA? Mian function of CEA is to exclude mets from GI primary

A

mUcinous tumours

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16
Q

How do you calculate RMI for ovarian cancer?

A

Menopausal status x serum CA125 x US score

17
Q

What biochemistry test should be requested when investigating ovarian canceR?

A

Serum albumin

18
Q

ascites/ bloating
pelvic mass/ bladder dysfunction
pleural effusion/shortness of breath

A

Ovarian cancer

19
Q

Patient with an RMI above what should be referred to hospital?

A

Above 200

20
Q

FIGO staging of ovarian cancer: confined to 1 or both ovaries

A

I

21
Q

FIGO staging of ovarian cancer: spread beyond pelkvis within the abdomen?

A

III

22
Q

FIGO staging of ovarian cancer: Spread to other pelvic organs e.g. uterus, fallopian tube

A

II

23
Q

FIGO staging of ovarian cancer: spread into other organs e.g. liver, lungs?

A

iv

24
Q

What should all women with high grade early stage Ia-Ib ovarian cancer ben considered for?

A

Chemotherapy

25
Q

For advanced disease ovarian cancer what is drug of choice for both single and combnation therapy?

A

Carboplatin (platinum drug)

26
Q

What are the most common extra-abdominal cancers that cause malignant bowel obstruction?

A

Breast
Melanoma
Lung