week 5 (skin and body movements, body flora, cartilage and skeletal system) Flashcards
integumentary system
The integumentary system helps maintain a constant body
temperature, protects the body, and provides sensory information
about the surrounding environment
Functions of the Integumentary System 1. Regulates body temperature. 2. Stores blood. 3. Protects body from external environment. 4. Detects cutaneous sensations. 5. Excretes and absorbs substances. 6. Synthesizes vitamin D.
what is the tissue of the epidermal layer like
the epidermis is the most superficial layer of the skin (what you touch)
it consists of keratinized straified squamous epithelium which means theres many layers of cells
generally the cells in the deepest layer are cubiodal and are continually dividing to produce cells that move to become part of the layer of cells above them
the most superficial celllayer consists of dead cells full of kertain
epidermis is avasular
stratum gerinativum (strutum basale)
The deepest layer of the epidermis is the stratum basale, composed of a single row of cuboidal or columnar keratinocytes. Some cells in this layer
are stem cells that undergo cell division to continually produce new kertaincytes
A distinctive feature of cells in this layer is the presence
of darkly staining granules of a protein called keratohyalin (ker′-
a-toˉ-HI
-
-a-lin), which assembles keratin intermediate filaments into
keratin. Also present in the keratinocytes are membrane-enclosed
lamellar granules (la-MEL-ar), which fuse with the plasma membrane
and release a lipid-rich secretion. This secretion is deposited in the
spaces between cells of the stratum granulosum, stratum lucidum, and
stratum corneum. The lipid-rich secretion acts as a water-repellent
sealant, retarding loss and entry of water and entry of foreign materials
stratum corneum
The stratum corneum consists on average of 25 to 30 layers of flattened
dead keratinocytes, but can range in thickness from a few cells in thin
skin to 50 or more cell layers in thick skin.
They are the final
product of the dif erentiation process of the keratinocytes. The cells
within each layer overlap one another like the scales on the skin of a
snake.
Its multiple layers of dead cells help the stratum corneum to protect
deeper layers from injury and microbial invasion
stratum lucidum
The stratum lucidum is present only in the thick skin of areas such as the
fingertips, palms, and soles.
It consists of four to six layers of flattened
clear, dead keratinocytes that contain large amounts of keratin and
thickened plasma membranes.
This probably provides an additional
level of toughness in this region of thick skin
stratum spinosum
Superficial to the stratum basale is the
stratum spinosum. This stratum
mainly consists of numerous keratinocytes arranged in 8–10 layers
This arrangement provides both strength and flexibility to the skin because of the bundle of kertain interfilaments and demosomes
kertainocytes
keratinocytes, which are arranged
in four or five layers and produce the protein keratin.
keratin is a tough, fibrous protein that helps protect the skin and underlying tissues from abrasions,
heat, microbes, and chemical
melanocytes
which develop from the ectoderm of a developing embryo and produce the pigment melanin
suboriferous gland
Throughout skin of most
regions of body, especially
skin of forehead, palms,
and soles.
Mostly in deep dermis
(sometimes in upper
subcutaneous layer).
secretion: Perspiration, which consists of water, ions (Na+ , Cl− ), urea, uric acid, ammonia, amino acids, glucose, and lactic acid
Regulation of body
temperature, waste removal,
stimulated during emotional
stress.
sebaceous gland (oil)
Prevent hairs from drying
out, prevent water loss from
skin, keep skin soft, inhibit
growth of some bacteria.
Largely in lips, glans penis, labia minora, and tarsal glands; small in trunk and limbs; absent in palms and soles.
Secretion Sebum
hair follicle
A hair follicle is a tunnel-shaped structure in the epidermis (outer layer) of the skin. Hair starts growing at the bottom of a hair follicle
stratum granulsom
At about the middle of the epidermis,
the stratum granulosum
consists of three to five layers of flattened keratinocytes that are
undergoing apoptosis.
apoptosis
apoptosis is an
orderly, genetically programmed cell death in which the nucleus
fragments before the cells die
dermis
connective tissue layer just below the epidermis
second major layer of skin, consists of two areas in the connective tissue
the layer adjacent to the basement membrane of the spidermal layer is called the papillary region. it consists of areolar connective tissue with a lot of elastic fibres
the reticular region is the deeper connective tissue layer which consisits of dense, irregular connective tissue (lots of collagen and elastic fibres)
fibroblasts
large, flat cells with
branching processes. They are present in all the general connective
tissues, and usually are the most numerous.
secrete fibers and
ground substance
elastic fibres
which are smaller in diameter than collagen fibers,
branch and join together to form a fibrous network within a connective
tissue. An elastic fiber consists of molecules of the protein elastin surrounded by a glycoprotein named fibrillin, which adds strength and
stability. Because of their unique molecular structure, elastic fibers are
strong but can be stretched up to 150% of their relaxed length without
breaking.
collagen fibres
are very strong and resist pulling or stretching, but they are not stif , which allows tissue
flexibility. The properties of dif erent types of collagen fibers vary
from tissue to tissue. For example, the collagen fibers found in cartilage and bone form dif erent associations with surrounding molecules
reticular region
Deeper portion of dermis consists
of dense irregular connective tissue with bundles ofthick collagen and some coarse elastic fibers.
Spaces between fibers contain some adipose cells, hair follicles, nerves, sebaceous glands, and sudoriferous
glands.
blood vessel (arteriole)
small-diameter blood vessel in the microcirculation that extends and branches out from an artery and leads to capillaries
blood vessel (venule)
venule is a small blood vessel in the microcirculation that allows deoxygenated blood to return from capillary beds to larger blood vessels called veins. Venules range from 8 to 100μm in diameter and are formed when capillaries come together. Many venules unite to form a vein
sensory receptors
sensory receptors can be found throughout the skin. they will receive stimulis from internal and external environment
subcutaneous layer
this layer consists of areolar and adipose tissues. Fibers that extend from the dermis anchor the skin to the subcutaneous layer, which in turn attaches to underlying fascia, the connective tissue around muscles and
bones. The subcutaneous layer serves as a storage depot for fat and contains large blood vessels that supply the skin
amino acids in relation to the skin
Amino acids are important nutrients required for wound healing promotion and repair of the damaged skin
glucose in relation to the skin
cause hormonal changes and other biologic dysfunction that lead to acne. Optimizing our metabolic fitness with a glucose monitoring program like Levels can help us make choices to minimize our body’s exposure to excess glucose (sugar), which may help prevent premature skin aging and acne
oxygen in relation to the skin
Oxygenation has to do with breathing and blood flow. On and in the skin, as for other tissues in the body, oxygen is essential to the health and maintenance of the cells
feedback loop for body temp
by
liberating sweat at its surface and by adjusting the flow of blood in the
dermis. In response to high environmental temperature or heat produced
by exercise, sweat production from eccrine sweat glands increases; the
evaporation of sweat from the skin surface helps lower body temperature. In addition, blood vessels in the dermis of the skin dilate (become
wider); consequently, more blood flows through the dermis, which
increases the amount of heat loss from the body. In
response to low environmental temperature, production of sweat from
eccrine sweat glands is decreased, which helps conserve heat. Also, the
blood vessels in the dermis of the skin constrict (become narrow), which
decreases blood flow through the skin and reduces heat loss from the
body. And, skeletal muscle contractions generate body heat.
membrane
selective barrier; it allows some things to pass through but stops others
membrane
selective barrier; it allows some things to pass through but stops others
serous membrane
A serous membrane or serosa lines a body cavity that does not open directly to the exterior and it covers the organs that are within the cavity. Serous membranes consist of areolar connective tissue covered by mesothelium
A mucous membrane or mucosa lines a body cavity that opens directly to the exterior. Mucous membranes line the entire digestive, respiratory, and reproductive tracts, and much of the urinary tract. They consist of a lining layer of epithelium and an underlying layer of connective tissue
The cutaneous membrane or skin covers the entire surface of the body and consists
of a superficial portion called the epidermis and a deeper portion
called the dermis. The epidermis consists of keratinized stratified squamous epithelium, which protects underlying tissues
synovial membranes
Synovial membranes line the cavities of freely movable joints (joint cavities). Like serous membranes,
synovial membranes line structures that do not open to the exterior.
Unlike mucous, serous, and cutaneous membranes, they lack an
epithelium and are therefore not epithelial membranes. Synovial
membranes are composed of a discontinuous layer of cells called
synoviocytes, which are closer to the synovial cavity
(space between the bones), and a layer of connective tissue
mucous membrane
a body cavity that opens directly to the exterior. Mucous membranes line the entire digestive, respiratory, and reproductive tracts, and much of the urinary tract. They consist of a lining layer of epithelium and an underlying layer of connective tissue
cutaenous membrane
The cutaneous membrane or skin covers the entire surface of the body and consists
of a superficial portion called the epidermis and a deeper portion
called the dermis. The epidermis consists of keratinized stratified squamous epithelium, which protects underlying tissues
cartilage
consists of a dense network of
collagen fibers and elastic fibers firmly embedded in chondroitin
sulfate, a gel-like component of the ground substance. Cartilage can
endure considerably more stress than loose and dense connective
tissues. The strength of cartilage is due to its collagen fibers, and its
resilience (ability to assume its original shape af er deformation) is
due to chondroitin sulfate.
connective tissue vs cartilage
cartilage does not have nerves or blood in its extracellular matrix
chondrocytes
Chondrocytes are the cells responsible for cartilage formation, and they are crucial for the process of endochondral ossification, which is useful for bone development.
lacuane
a cavity or depression, especially in bone
perichondrium
s a layer of dense irregular connective tissue that surrounds the cartilage of developing bone. It consists of two separate layers: an outer fibrous layer and inner chondrogenic layer.
body flora
flora is the term used to describe the microorganisms that exist on or within the human body, such as the gut flora or the skin flora
host/parasite realtionship
demostarted when the bacteria causes a mild to sereve infection. the bacterical species gains a foothold in the body, repilcates and initates a defensive response by the host.
bacterica causes the disease which is called a pathogen
OR
bacteria that have gained a foothold on a membrane surface nut do not intatie defensibe response are normal body flora.
lactobacilli (protection)
live on the mucous membrane lining in the vagina. their presence maintains an acid pH i the vagina during reproductive year. This high pH has an affect on pathogens