Week 5: Receptors of inflammatory mediators Flashcards
1
Q
Histamine
A
H1 (Bronchoconstriction, Contraction of GI smooth muscle, Increased capillary permeability (wheal), Pruritis (itch) and pain, Release of catecholamines from the adrenal medulla) H2 (Gastric acid secretion), H3 (Histaminergic nerve terminals) and H4 (can regulate immune responses)
2
Q
PGE2
A
EP1 through 4
3
Q
PGD2
A
DP
4
Q
PGF2
A
FP
5
Q
TXA2
A
TP
6
Q
PGI2
A
IP
7
Q
LTB4
A
LTB4 receptor
8
Q
LTC4, LTD4, LTE2
A
CysLTR1 or LTD4, Cys LTR2 or LTC4
9
Q
Kinins
A
B1 (chronic inflammation), B2 (vasodilation, permability, pain, sodium excretion)