Week 4 high yield buzzwords Flashcards by Weston Tardy | Brainscape

Q

Benzene exposure:

A

Secondary AML

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

inv(16):

A

APML

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

11q23

A

monocytic AML

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

t(15;17)

A

AML M3

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Don’t let the sun set on…..

A

AML M3

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CD5+
CD19+
CD20+
CD23+

A

CLL

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CD5+
CD23-
cyclin D1+

A

Mantle cell lymphoma

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

ZAP-70+

A

Ig Vh mutation – poor prognosis

CLL

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

13q-

A

Smudge cell CLL

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Parvovirus on DDx

A

red cell aplasia

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

High L-selectin and CCR7

A

Naive CTL-P in lymph node

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

High CD44 and LFA-1

A

Effector CTL

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

LFA-1 binds:

A

ICAM

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CD56-low

A

CTL w/granules – best killer

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CD56-high

A

CTL w/o granules – release cytokines (INF-y)

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CD16 (FcyRIIIA), NKRs

A

NK cells

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

NKG2A (CD94)

A

NK cell inhibitory receptor

**trumps everything

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

KIR2DS1

A

NK cell activating receptor

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Basophilia

A

CML

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Philadelphia chromosome

A

CML

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Neutrophilic leukocytosis

A

CML

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

t(9;22)

A

CML

BCR-ABL

Philadelphia

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Jak-2

A

Polycythemia vera

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Plethora (flushing)

A

Polycythemia vera

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

High Platelets in YOUNG WOMEN:

A

Essential Thrombocythemia

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Teardrop RBCs

A

Chronic Myelofibrosis

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

LUQ fullnes

A

Chronic myelofibrosis

HUGE spleen

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

BCR-ABL

A

CML

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

Wnt-B catenin

A

CML Blast phase

How well did you know this?

1

Not at all

2

3

4

5

Perfectly

Q

CEBPa

A

promotes myeloid differention

**blocked in CML Blast phase

Q

Coil-coil domain/ tyrosin 177

A

BCR

Q

Myristate

A

ABL

inhibitory

lost in CML

Q

Stat5

A

transcription factor acting w/o GM-CSF signaling in CML

Q

BCR-ABL specific tyr-kinase inhibitor

A

Imatinib

CML

Q

Osteolytic lesions

A

Multiple myeloma

Q

Bence-Jones proteins

A

Multiple Myeloma

Q

Rouleaux

A

Multiple Myeloma

Q

Amyloid in BM

A

Multiple Myloma

Q

Flame cells

A

multiple myeloma

Q

Russel bodies

A

multiple myeloma

Q

Dutcher bodies

A

multiple myeloma

Q

Mott cells

A

multiple myeloma

Q

Plasma cell tumor with IgM

Retinal involvement

A

Waldenstrom macroglobulinemia

Q

anemia

bone pain

renal failure

A

multiple myeloma

Q

small, mature lyphocytes

A

CLL

Q

B-cells w/CD5+

A

CLL

Q

bcl-2

A

CLL

immortalizes cells

Q

TRAP+

A

Hairy cell Leukemia

Q

CD25+
CD11c+
CD5-

A

Hairy Cell Leukemia

Q

Slepomegaly without lymphadenopathy

A

Hairy cell

Prolymphocytic

Q

Large granulated lymphocytes

A

T-cell

Large granulated lymphocyte leukemia

Q

Tingible body macrophages

A

Follicular Hyperplasia

Burkitt Lymphoma

Q

Partial effacement

A

Interfollicular Hyperplasia

Q

Small lymphocitic lymphoma

A

CLL

Q

H. pylori

A

MALT lymphoma

Q

t(11;14)

A

Mantle Cell Lymphoma

Q

t(14;18)

A

Follicular lymphoma

Q

butt cels

A

Follicular lymphoma

Q

paratrabecular aggregate

A

Follicular lymphoma

Q

Cerebriform lymphocytes

A

Mycosis fungoides

Q

Psorias looking

A

Mycosis fungoides

Q

Pautrier microabscess

A

Mycosis fungoides

Q

Large B-cells

A

Diffuse Large cell Lymphoma

Q

Teenage male with mediastinal mass

A

Lymphoblastic lymphoma

same as ALL

Q

t(8;14)

A

Burkitt Lymphoma

Q

Starry-sky pattern

A

Burkitt lymphoma

Q

HTLV-1

A

Adult T-cell Leukemia/lymphoma

Q

Reed-Sternberg cell

A

Hodgkin Lymphoma

Q

Popcorn cells

A

Nodular Lymphocytic-Predominance Hodgkin Lymphoma

Q

Lacunar cells

A

Nodular Sclerosis Hodgkin Lymphoma

Q

Collagen/reticulin background

A

Lymphocyte depletion Hodgkin Lymphoma

Q

Lung disease (drug)

A

Bleomycin

Q

anti-CD20 drug

A

Rituximab