Week 4 Day 1 Flashcards
Le chatelier’s principle
can be used to predict the affect of change in conditions on a chemical equilibrium
Keq= [Ceq]c * [Deq]d/[Aeq]a * [Beq]b
Dissociation of water
[H+]=[OH-] = 1.0 x 10-7
acid
molecule that donates a H+
base
molecule that accepts an H+
conjugate base
what is left after an acid has donated a proton
conjugate acid
formed by a base accepting a hydrogen
Henderson-Hasselbalch equation
pH = pKa + log([A-] / [HA])
Used to calculate the pH of a buffer and states the pH of a buffer is equal to the pKa of the weak acid plus the log of the ratio of the concentration of the conjugate base [A-], divided by the concentration of the acid [HA]
buffer
a solution that can resist change in pH upon addition of acidic or basic components
Usually consists of a weak acid and its conjugate base
Normal values:
pH
CO2
HCO3
pH: 7.4 (7.35-7.45)
CO2: 40 mmhg (35-45)
HCO3: 24 mM (20-28)
acute respiratory acidosis
Increased CO2
decreased pH
increased HCO3-
normal BE
chronic respiratory acidosis
increased CO2
close to normal pH
very increased HCO3-
> +2 BE
acute metabolic acidosis
decreased CO2
decreased HCO3- or increased H+
decreased pH
negative <-2 BE
Chronic metabolic acidosis
decreased CO2
decreased HCO3-
about normal pH
negative <-2 BE
Acute respiratory alkalosis
decreased CO2
decreased HCO3-
increased pH
normal BE
chronic respiratory alkalosis
decreased CO2
very decreased HCO3-
about normal pH
negative <-2 BE