WEEK 4 Flashcards
arterial blood
lithium heparin
ABG
can yield a hydrogen ion (H)
donor
acids
can yield hydroxyl ions
acceptor
base
weak acid
weak base, salt
bicarbonate (HCO3)
buffer
Principal mammalian buffer system
BICARBONATE-CARBONIC ACID
BUFFER SYSTEM
HCO3>H2CO3
unstable, changing to H2O and CO2 in
fluid
H2CO3, carbonic acid
Phosphate form that
acts as a buffer
2,3-diphosphoglycerate
It increases the amount of NaHCO3 in ECF
(more alkaline)
PHOSPHATE BUFFER SYSTEM
16% of the non-bicarbonate buffer value of
Erythrocytes
PHOSPHATE BUFFER SYSTEM
Maintains pH level (Venous and Arterial Blood)
HEMOGLOBIN-OXYHEMOGLOBIN
BUFFER SYSTEM
1 gram of Hemoglobin carries – of
Oxygen
1.39 mL
Proteins can exist in 2 forms: H+ protein, B
Protein
PROTEIN BUFFER SYSTEM
Capability to bind or release excess Hydrogen
as required
PROTEIN BUFFER SYSTEM
Plasma proteins (Charges on their surface)
* pH > pI – charge
-
Plasma proteins (Charges on their surface)
* pH < pI – charge
+
The second largest fraction of the anions in
the plasma. It includes the ionized
bicarbonate (HC03), carbonate and the
carbamino compounds.
BICARBONATE (HCO3)
This fraction of blood, plasma or serum
Includes the undissociated carbonic acid and
the physically dissolved anhydrous C02
CARBONIC ACID (H2CO3 )
The pressure or tension exerted by C02 gas
dissolved in blood. It is an index of efficiency
of gas exchange in the lungs and not a
measure of C02 concentration in the blood.
PARTIAL PRESSURE OF C02
(pC02)
Normal range is 35 - 45 mmHg
PARTIAL PRESSURE OF C02
(pC02)
an
index of the amount of CO2 that can be bound
by serum, plasma, or whole blood as HCO3 at a
pCO2 of 40 mmHg at 25 degrees Celcius.
CARBON DIOXIDE COMBINING
POWER (CO2 combining power)