WEEK 4 Flashcards

1
Q

detected a
heat precipitate in samples of acidified urine from patients
suffering from “Mollities osseum

A

bence jones

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2
Q

first tumor antigen

colon cancer

A

CEA

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3
Q

true negative rate

A

specificity

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4
Q

true positive rate

A

sensitive

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5
Q

e Ki-67 (proliferation index)

A

prognostic/diagnostic

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6
Q

AFP, CEA

A

Category

Oncofetal antigens

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7
Q

Catecholamines,
Calcitonin, b-hCG

A

Hormones

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8
Q

CA 125, CA 15-3, CA
19-9, CA 72-4, PSA

A

Glycoproteins

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9
Q

VMA, HIAA

A

Metabolites

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10
Q

Polyoma, SV 40

A

Viral antigens

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11
Q

H-2 k antigen

A

MHC-related
antigens

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12
Q

PAP, NSE, PLAP

A

Enzymes

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13
Q

c-myc, c-erbB2

A

Oncogene products

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14
Q

Immunoglobulins,
b-2M

A

Proteins

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15
Q

C-reactive protein,
ferritin

A

Acute-phase
proteins

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16
Q

ESR, viscosity

A

Inflammatory
makers

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17
Q

Desmin, vimentin

A

Intermediate
filament
components

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18
Q

Steroids, Catecholamines

A

Adrenal carcinoma

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19
Q

CA 15-3, CA 27.29 Serology / Tissue IHC M, R
ER / PR / Her-2neu

A

Breast

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20
Q

5-HIAA
URINE SAMPLE

A

Carcinoid

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21
Q

CEA, CA 19-9

A

Colorectal, stomach, pancreas

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22
Q

b-hCG

A

Choriocarcinoma

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23
Q

AFP, b-hCG Serology / Tissue IHC D, P, M
LDH, PLAP (Seminoma)

A

Germ cell tumors

24
Q

AFP

A

Hepatoma

25
Q

LDH
Cytogenetic alterations Genetic analysis D

A

Lymphomas

26
Q

Tyrosinase

A

Melanoma

27
Q

Immunoglobulins

A

Myeloma

28
Q

CA 125

A

Ovarian

29
Q

PSA

A

Prostate

30
Q

Cytogenetic alterations Genetic analysis D

A

Sarcomas

31
Q

Thyroglobulin Serology / Tissue IHC S, M
Calcitonin (medullary carcinoma)

A

Thyroid

32
Q

BENIGN
Viral hepatitis, liver injury, IBD, pregnancy

A

AFP

33
Q

BENIGN
Testicular failure, marijuana smokers, pregnancy

A

b-hCG

34
Q

BENIGN
Smokers, IBD, hepatitis, cirrhosis, pancreatitis,
gastritis

A

CEA

35
Q

BENIGN
Peritoneal irritation, endometriosis, pelvic
inflammatory disease, hepatitis, pregnancy

A

CA 125

36
Q

BENIGN
Prostatitis, benign prostatic hyperplasia

A

PAP / PSA

37
Q

Bone cancer

A

Alkaline phosphatase

38
Q

Chromogranin A

A

Carcinoid

39
Q

SCC-A

A

Cervical cancer

40
Q

CA 72-4

A

Gastric carcinoma

41
Q

AFP

A

HCC

42
Q

Leukemia

A

TdT

43
Q

Lung cancer

A

NSE

44
Q

Lymphoma

A

b2M

45
Q

Medullary thyroid cancer

A

Calcitonin

46
Q

Non-seminomatous
testicular tumor

A

AFP

47
Q

Pheochromocytoma

A

Metanephrine

48
Q

PSA
NSE

A

Isoenzymes

49
Q

LASA-P
SCC-A
TAG 72
Immunoglobulins

A

Cellular components/products

50
Q

Pheochromocytoma, neuroblastoma

A

Chromogranin A

51
Q

Pituitary cancer

A

IGF- 1

52
Q

Gastric carcinoma

A

TAG 72

53
Q

ECTOPIC
Gastrointestinal, renal, breast, bladder
and ovary carcinoma

A

AFP

54
Q

ECTOPIC
Carcinoma of lung, islet cell, carcinoid,
breast and ovary; medullary carcinoma;
pheochromocytoma

A

Calcitonin

55
Q

ECTOPIC
For endocrine tumors (medullary thyroid
carcinoma, anterior pituitary adenoma,
pancreatic islet-cell carcinoma)

A

Chromogranin A

56
Q

ECTOPIC
Gastric and pancreatic carcinomas,
hepatoma, ovarian adenocarcinoma,
germinal-cell tumors of the testis

A

b-hCG

57
Q

ECTOPIC
WD thyroid carcinoma

A

Thyroglobulin