WEEK 4

Question 1

detected a
heat precipitate in samples of acidified urine from patients
suffering from “Mollities osseum

Answer 1

bence jones

Question 2

first tumor antigen

colon cancer

Answer 2

CEA

Question 3

true negative rate

Answer 3

specificity

Question 4

true positive rate

Answer 4

sensitive

Question 5

e Ki-67 (proliferation index)

Answer 5

prognostic/diagnostic

Question 6

AFP, CEA

Answer 6

Category

Oncofetal antigens

Question 7

Catecholamines,
Calcitonin, b-hCG

Answer 7

Hormones

Question 8

CA 125, CA 15-3, CA
19-9, CA 72-4, PSA

Answer 8

Glycoproteins

Question 9

VMA, HIAA

Answer 9

Metabolites

Question 10

Polyoma, SV 40

Answer 10

Viral antigens

Question 11

H-2 k antigen

Answer 11

MHC-related
antigens

Question 12

PAP, NSE, PLAP

Answer 12

Enzymes

Question 13

c-myc, c-erbB2

Answer 13

Oncogene products

Question 14

Immunoglobulins,
b-2M

Answer 14

Proteins

Question 15

C-reactive protein,
ferritin

Answer 15

Acute-phase
proteins

Question 16

ESR, viscosity

Answer 16

Inflammatory
makers

Question 17

Desmin, vimentin

Answer 17

Intermediate
filament
components

Question 18

Steroids, Catecholamines

Answer 18

Adrenal carcinoma

Question 19

CA 15-3, CA 27.29 Serology / Tissue IHC M, R
ER / PR / Her-2neu

Answer 19

Breast

Question 20

5-HIAA
URINE SAMPLE

Answer 20

Carcinoid

Question 21

CEA, CA 19-9

Answer 21

Colorectal, stomach, pancreas

Question 22

b-hCG

Answer 22

Choriocarcinoma

Question 23

AFP, b-hCG Serology / Tissue IHC D, P, M
LDH, PLAP (Seminoma)

Answer 23

Germ cell tumors

Question 24

AFP

Answer 24

Hepatoma

Question 25

LDH
Cytogenetic alterations Genetic analysis D

Answer 25

Lymphomas

Question 26

Tyrosinase

Answer 26

Melanoma

Question 27

Immunoglobulins

Answer 27

Myeloma

Question 28

CA 125

Answer 28

Ovarian

Question 29

PSA

Answer 29

Prostate

Question 30

Cytogenetic alterations Genetic analysis D

Answer 30

Sarcomas

Question 31

Thyroglobulin Serology / Tissue IHC S, M
Calcitonin (medullary carcinoma)

Answer 31

Thyroid

Question 32

BENIGN
Viral hepatitis, liver injury, IBD, pregnancy

Answer 32

AFP

Question 33

BENIGN
Testicular failure, marijuana smokers, pregnancy

Answer 33

b-hCG

Question 34

BENIGN
Smokers, IBD, hepatitis, cirrhosis, pancreatitis,
gastritis

Answer 34

CEA

Question 35

BENIGN
Peritoneal irritation, endometriosis, pelvic
inflammatory disease, hepatitis, pregnancy

Answer 35

CA 125

Question 36

BENIGN
Prostatitis, benign prostatic hyperplasia

Answer 36

PAP / PSA

Question 37

Bone cancer

Answer 37

Alkaline phosphatase

Question 38

Chromogranin A

Answer 38

Carcinoid

Question 39

SCC-A

Answer 39

Cervical cancer

Question 40

CA 72-4

Answer 40

Gastric carcinoma

Question 41

AFP

Answer 41

HCC

Question 42

Leukemia

Answer 42

TdT

Question 43

Lung cancer

Answer 43

NSE

Question 44

Lymphoma

Answer 44

b2M

Question 45

Medullary thyroid cancer

Answer 45

Calcitonin

Question 46

Non-seminomatous
testicular tumor

Answer 46

AFP

Question 47

Pheochromocytoma

Answer 47

Metanephrine

Question 48

PSA
NSE

Answer 48

Isoenzymes

Question 49

LASA-P
SCC-A
TAG 72
Immunoglobulins

Answer 49

Cellular components/products

Question 50

Pheochromocytoma, neuroblastoma

Answer 50

Chromogranin A

Question 51

Pituitary cancer

Answer 51

IGF- 1

Question 52

Gastric carcinoma

Answer 52

TAG 72

Question 53

ECTOPIC
Gastrointestinal, renal, breast, bladder
and ovary carcinoma

Answer 53

AFP

Question 54

ECTOPIC
Carcinoma of lung, islet cell, carcinoid,
breast and ovary; medullary carcinoma;
pheochromocytoma

Answer 54

Calcitonin

Question 55

ECTOPIC
For endocrine tumors (medullary thyroid
carcinoma, anterior pituitary adenoma,
pancreatic islet-cell carcinoma)

Answer 55

Chromogranin A

Question 56

ECTOPIC
Gastric and pancreatic carcinomas,
hepatoma, ovarian adenocarcinoma,
germinal-cell tumors of the testis

Answer 56

b-hCG

Question 57

ECTOPIC
WD thyroid carcinoma

Answer 57

Thyroglobulin