Week 3.4 Autoimmune Pathologies Flashcards
what is SLE
systemic Lupus erythematosis
give an overview of the condition
AA and latino and asian women, aged 15 to 45, with women being 9-10x more likely than men
is there a cure for SLE
no
how do you self manage SLE
avoid exposure to sunlight avoid smoking stress management prolonged rest at night (12 hours) regular exercise
what are signs and symptoms of SLE
joint inflammation, kidney disease, skin rashes, fatigue, muscle pain, fever, loss of hair, Raynaud’s disease, seizures, sensitivity to the sun, swelling (edema in the legs or around the eyes)
SLE may also affect
heart, lungs, blood and brain
how do you diagnose SLE
blood tests and tissue biopsy
how do you treat SLE
corticosteroid creams,
NSAIDs,
antimalarial medications,
corticosteroid pills or IV
is SLE a medical emergency
no, but you need a consultation,
how do you do PT for a patient with SLE
manage their energy levels, ask them how they feel because they will often be fatigued
what is dermatomyositis
pink cheeks
purple hue over the eyelids
red skin rashes (elbows, knuckles, knees)
muscle inflammation, weakness and ashiness.
what happens to symptoms over time with dermatomyositis
flu like symptoms, with fever and chills and symptoms getting worse over time, to the point that they cannot stand or climb stairs
what is the prognosis of dermatomyositis
good, if detected early, treatment will improve outcomes. Rarely recurrent, but you may need meds for up to 2 years
how might dermatomyositis present
skin manifestation in the absence of muscle weakness, and subtle skin manifestations like subtle erythema
how do you differential between lupus and dermatomyositis
lupus spares the naso- labial region, and in dermatomyositis, you have it every where, including the nose and mouth area.
what is scleroderma
hardening of the skin that affects different body parts
what is the cause an prognosis of scleroderma
cause is unknown, prognosis is no cure
what is the incidence of scleroderma
localized form in child systemic in adults women more common (4:1) genetic age 25-55
how do you manage scleroderma
medications are greatly variable
how do you handle scleroderma
prompt referral, minimize symptoms and reduce irreversible damage
how can you tell if you have limited systemic scleroderma
CREST
C: calcinosis
R: Raynaud
E: esophageal dysfunction
S: Sclerodactyly (hardening of the skin and hands that cause the fingers to curl in like claws)
T: telangiectasia (widened venules that cause red lines on the skin, like webs)
how do you diagnose scleroderma
blood test and other test that check organs and skin
what pulmonary condition can you get with scleroderma
pulmonary HTN with SOB
What is psoriatic disorder
speeds up the life cycle of skin cells (get rapidly appearing scales and patches) IDIOPATHIC.
what are comorbidites with psoriatic disease
autoimmune thyroid disease, diabetes, metabolic syndrome and psoriatic arthritis
what are the signs and symptoms of psoriatic disease
- red patches of the skin, covered with thigh and silvery scales
- small scaling spots
- dry cracked skin that bleeds
- itching burning and soreness
- thickened or pitted or ridged nails
- swollen and stiff joints
how does psoriatic disease manifest in the clinic
- discomfort and pain,
- difficulty with routine tasks
- concern about the patients skin
- joint pain, swelling, inability to do ADLs
what predisposes you to psoratic disease
- infection (strep or skin infections)
- injury to the skin, cut scrape, bug bite, severe burn
- stress
- smoking
- alcohol consumption
- Vit D deficiency
- certain meds (lithium)
what is lithium prescribed for
bipolar disorders, HBP, beta blockers, antimalarial drugs, and iodides.
how do you manage psoriatic disease
diet, exercise, weight control, avoid smoking, meds, monitor for depression
what are we looking for with depression
difficulty sleeping, anxiety, fatigue
is psoriatic an emergency
no, but can life threatening: damage organs
