Week 3 Pregnancy (Q. 16) Flashcards

1
Q

True or False

Mild Ischemia is a common symptom with cardiovascular changes in pregnant women?

A

ECG changes show a Left Axis Deviation and flattening of t waves suggestive of mild ischaemia - seen in 15% of women

There is a rapid increase in CO and HR of approximately 15bpm.

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2
Q

There is a rapid increase in CO and HR by 15bpm. This is due to neuron-hormonal influences, increases in ______ _____, decreased peripheral _______ and the fact that the feto-placental units acts like an arterio-venous fistula

A. Blood Volume; resistance
B. HR; constriction
C. Blood Volume; constriction
D. HR; dilation

A

A. Blood Volume. Resistance

Progesterone relaxes vascular smooth muscle = vasodilation –> decrease PVR

Oestrogen Stimulates angiogenesis and collagen in tunica media of veins = increased distensibility –> decrease PVR

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3
Q

What is not a cardiovascular sign and symptom of pregnancy changes

a. Increased BV 35-45%
b. Vasodilation in skin for temp control
c. Decreased Heart Size to decrease SBP
d. Oedema (decrease venous return from extremeties)
e. Changes to heart sounds - murmur may develop

A

C. Decreased Heart Size to decrease SBP

Heart increases in size by 12%

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4
Q

Respiratory Symptoms

Due to the increased red blood cell count, we can expect to see respiratory changes. What is not an expected change

a. Increased TV, Rate and Alveolar Ventilation
b. Increased oxygen consumption
c. Carbon dioxide content increases
d. Hyperaemia and oedema of the respiratory tract

A

c. Carbon dioxide content Increases

When Carbon Dioxide actually decreases

Hyperaemia and oedema of nasal, sinus, nasopharyngeal and lower respiratory tract =

  • Nosebleeds common
  • Increased nasal stuffiness
  • Decreased hearing
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5
Q

The profound effect of _________ on the smooth muscle in the GI causes reflux, constipation and bloating?

A. Progrestrone
B. Testostrone
C. Prolactin
D. Estrogen

A

A. Progesterone

Hormones cause relaxation of the esophageal sphincter. This is a tight circular band of muscle at the top of the stomach. This allows partially digested food and stomach acids to backflow, or reflux, into the esophagus. In addition, progesterone also slows the digestive process

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6
Q

What is the role of lactogen (released from the placenta)?

A. Increase in glucose production in the fetus
B. Increase glucose delivery to the fetus
C. decrease glucose and increase ketones for energy
D. protect the developing fetus from diabetes

A

B. Increase glucose delivery to the fetus

Fetus require 3x glucose compared to adult
Lactogen has an anti-insulin effect that prevents glucose uptake in the mother –> more glucose to the fetus –> mother has glycosuria

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7
Q

Overall is the metabolism of pregnancy in an anabolic or catabolic state?

A

Pregnancy in general is an anabolic state.

Food intake and appetite increases
Activity decreases
The first half of pregnancy is primarily anabolic
The second half of pregnancy has some catabolic states

Overall = Anabolic

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8
Q

What is colostrum milk?

A

Colostrum is the first form of milk produced by the mammary glands;

Rich in Vitamin A, Protein, Minerals and IgA
Released 2 - 3 days
Followed by normal milk production

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9
Q

Why must Gestational Hypertension Headaches be investigated in pregnant women?

A

Gestational hypertension can lead to a serious condition called preeclampsia, also referred to as toxemia.

Other Headache causes are;

  • Brain Tumours (often 1st trimester)
  • Spontaneous Subarachnoid Haemorrhage
  • Muscle Contractions
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10
Q

What is Hyperemesis Gravidarum?

A

Hyperemesis can be defined as intractable vomiting resulting in 5% loss in pre-pregnancy weight, dehydration, disturbance of electrolytes, ketosis and need for admission to hospital.

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11
Q

When is the common time frame for pregnancies to fail?

A. 3 - 6 Weeks
B. 6 - 9 Weeks
C. 9 - 12 Weeks
D. 12 - 15 Weeks

A

B. 6 - 9 Weeks

Approximately 20% of clinically recognized pregnancies end in miscarriage and this increases to nearly 50% aged over 40 yrs

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12
Q

Vaginal bleeding, closed cervical os and fetal cardiac activity are associated with which type of miscarriage?

A. Threatened
B. Missed
C. Inevitable
D. Incomplete
E. Complete
A

A. Threatened

When your body is showing signs that you might miscarry, that is called a ‘threatened miscarriage’. You may have a little vaginal bleeding or lower abdominal pain. It can last days or weeks and the cervix is still closed.

The pain and bleeding may go away and you can continue to have a healthy pregnancy and baby. Or things may get worse and you go on to have a miscarriage.

There is rarely anything a doctor, midwife or you can do to protect the pregnancy.

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13
Q

‘Vaginal bleeding, dilated cervical os and some products of conception expelled and some remain.’

These signs/symptoms are associated with which type of miscarriage?

A. Threatened
B. Missed
C. Inevitable
D. Incomplete
E. Complete
A

D. Incomplete

Sometimes, some pregnancy tissue will remain in the uterus. Vaginal bleeding and lower abdominal cramping may continue as the uterus continues trying to empty itself. This is known as an ‘incomplete miscarriage’.

Your doctor or midwife will need to assess whether or not a short procedure called a ‘dilatation of the cervix and curettage of the uterus’ is necessary to remove any remaining pregnancy tissue.

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14
Q

Vaginal bleeding;
Dilated cervical os;
Products of conception seen/felt at or above cervical os

These signs/symptoms are associated with which type of miscarriage?

A. Threatened
B. Missed
C. Inevitable
D. Incomplete
E. Complete
A

C. Inevitable

Inevitable miscarriages can come after a threatened miscarriage or without warning. There is usually a lot more vaginal bleeding and strong lower stomach cramps. During the miscarriage, your cervix opens and the developing fetus will come away in the bleeding

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15
Q

No vaginal bleeding;
closed cervical os;
no fetal cardiac activity or an empty sac

These signs/symptoms are associated with which type of miscarriage?

A. Threatened
B. Missed
C. Inevitable
D. Incomplete
E. Complete
A

B. Missed (Baby has died but stayed in uterus)

If you have a missed miscarriage, you may have a brownish discharge. Some of the symptoms of pregnancy, such as nausea and tiredness, may have faded. You might have noticed nothing unusual. You may be shocked to have a scan and find the baby has died.

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16
Q

Vaginal bleeding or none;
Closed cervical os;
products of conception completely expelled

These signs/symptoms are associated with which type of miscarriage?

A. Threatened
B. Missed
C. Inevitable
D. Incomplete
E. Complete
A

E. Complete

A complete miscarriage has taken place when all the pregnancy tissue has left your uterus. Vaginal bleeding may continue for several days. Cramping pain much like labour or strong period pain is common – this is the uterus contracting to empty.

17
Q

Thalidomide in the 1950s was used for treating nausea and vomiting during pregnancy. Why is it no longer used?

A

Thalidomide use during pregnancy to babies born with severe limb abnormalities;

  • ­phocomelia (hands or feet are attached close to the trunk)
  • dysmelia (limb reduction or deficiency)
  • amelia (absence of all four limbs)
  • bone hypoplasticity

and other congenital defects

  • ear,
  • heart,
  • internal organs
18
Q

What changes occur to the lung/airways during pregnancy?

A
  • The diaphragm has pressure applied from uterus = discomfort in breathing
  • Progesterone relaxes ligaments in the ribs allowing for increased tidal and minute volume.
  • This leads to a decreased level of c02 in the blood that = respiratory alkalosis. = enhanced gas exchange across the placenta = fetus easier to get oxygen.
  • Progesterone and relaxin may cause pain in ribs due to shifting ligaments.
  • Estrogen causes increased vascularization, capillary engorgement in the upper airway tract.
  • This = nasal stuffiness, sinus congestion and nosebleeds (epistaxis)
19
Q

What changes occur to the kidneys during pregnancy?

A
  • Kidneys increase in size to compensate for the increased urinary output
  • Progesterone causes Hypermotility of ureters = urinary stasis = increased risk of UTI
  • Increased blood flow = increased GFR and Urinary output
  • Growing uterus places more pressure of bladder to also increase urinary frequency.
20
Q

What hormonal changes occur during pregnancy?

A

Estrogen and Progesterone steadily rise leading to anatomical and physiological changes.

21
Q

What ligamental changes occur during pregnancy?

A
  • Waddling Gait
  • This is caused by progesterone and relaxin having an effect on the ligaments in the sacroiliac joint and symphysis pubis in preparation for childbirth. This may also result in pain.
22
Q

What GI changes occur during pregnancy?

A
  • Smooth muscle relaxation and decreased peristalsis = constipation and bloating
  • Progesterone causes the relaxation of the lower esophageal sphincter = gastric reflux and heartburn.
23
Q

What changes in mood occur due to oestrogen and progesterone changes?

A

They may experience irritability, anxiety, depression, decreased concentration and mental fogginess.

Fatigue and sleep deprivation may also be present, sleep deprivation may also increase due to pain levels.

24
Q

What changes occur to the breast/skin due to oestrogen and progesterone changes?

A
  • Increase in size, tingling, fullness and tenderness
  • Estrogen triggers the anterior pituitary gland -> Release of prolactin = responsible for milk production in the boobies
  • Progesterone inhibits prolactin until baby is born and the need for milk is there.
  • Nips get dark due to melanocytes from anterior pituitary.
  • They also get linea nigra (dark line running from umbilicus to the pubis.)
25
Q

What changes occur to the thyroid gland during pregnancy?

A
  • Increase of stimulation and release to increase cellular basal metabolic rate to keep up with the demands of pregnancy.
26
Q

What weight changes occur during pregnancy?

A

Weight gain of 10 - 15kg

- Increase blood volume, fetus, fat stores, uterus, placenta.

27
Q

What cardiovascular changes occur during pregnancy?

A

Physiological anemia

  • Increase blood volume
  • RBC and plasma, with plasma having a significant increase
  • Increased Hematocrit = more plasma than RBC ratio

Heart rate increase = increase cardiac output

Hypertrophy of heart

BP decreases due to progesterone dilating blood vessels.

Uterus enlarges pushing heart upwards and leftwards

Uterus applies pressure on pelvic veins

  • This results in varicose veins
  • Swelling in lower legs and ankles

When supine, uterus presses on inferior vena cava

  • Less blood returns to the right atrium resulting in hypotension.
  • Elevate right side to prevent this

Hypercoagulable state due to Oestrogen increasing = less bleeding occurs at the time of birth. Oestrogen also inhibits the activation of Antithrombin 3.
- This also increases the risk of varicose veins and PE’s to occur.