Week 3 - Pharm Calculations Flashcards
Dose: The _______ of drug to be delivered to a patient to achieve an ________ effect
quantity, intended
A drug dose is expressed as ?
Single dose, daily dose, total dose
Single dose: Amount taken at _______ ______.
One time
Daily dose: Amount taken ________.
Daily
Dosage rate: should be expressed in ?
milligrams per kilograms (or milligrams per pound).
Dosage regimen is the _________ of dosing (e.g. three time daily for 7 days).
schedule
Drug doses are based on:
- ________ and __________ activity: ______
- _________ and __________ properties: Hydrophilic, lipophilic
- Dosage _________ used: Tablet, capsule, transdermal patch, etc
- ________ of Administration: PO, IV, etc
- _________ factors: Age, weight, body surface, liver and kidney function, etc
Biochemical, pharmacologic, ADME, Physical, chemical, form, Route, Patient
How do you calculate a drug dose?
Example: If a 20-kg dog is to be given amoxicillin at the rate of 10 mg/kg and injectable amoxicillin at a concentration of 100 mg/mL is available, the dosage calculation would be as follows:
2 mL
Example: a 20-kg dog is to be given amoxicillin at the rate of 10 mg/kg and injectable amoxicillin at a concentration 100 mg amoxicillin tablets are available, the formula becomes as follows:
2 tablets
Because most scales used to weigh animals provide the weight in pounds, a conversion must be made from pounds to kilograms:
If the order is to just “give a dog 300 mg of amoxicillin”, then the ordered amount is simply divided by the ___________ of the drug to determine the amount to be administered
concentration
Usually, you need to calculate the _______ of a dose, the ________ of doses, or the _______ quantity of drug to be dispensed.
size, number, total
How many teaspoonfuls would be prescribed in each dose of an elixir if 180 mL contained in 18 doses?
180/18 = 10 mL
10 mL = 2 teaspoonfuls
How many mL of a liquid would you provide a patient with 2 tablespoonfuls twice a day for 8 days?
30 x 32 = 960 mL
2 tbsp = 30 mL
32 doses needed
Total dose = size of dose x number of doses
1 kg = _______ g?
1000g
1 kg = ________ lb?
2.2 lb
1 g = ________ mg
1000