Immunostimulants Flashcards
IMMUNOPHARMACOLOGY is defined as a part
of pharmacology that deals with drugs _____ on ________
system, and, in addition, with the pharmacological actions of
substances _________ from the _______ system.
action, immune, derived, immune
Immune System : normally occurring protective mechanism that helps the body defend itself against potentially harmful agents (“immunis” = safe)
▪ May perceive normally harmless substances, such as ______ or
the person’s own body ________, as harmful invaders and try to eliminate them (_______, _______ disease)
▪ May be ______ or become _____ as a consequence of ____________ influences such as tumor microenvironment (______).
allergens, tissues, allergy, autoimmune, weak, weak, suppressive, cancer
List the primary lymphoid tissues
Bone marrow
Thymus
Bone marrow contains ___________ hematopoietic stem cells
pluripotent
Thymus is the center of?
T-cell maturation
List the secondary lymphoid tissues
Spleen
Lymph nodes
The spleen is the center of blood ________/____, ______ system
filtration, iron, immune, If you remove spleen, animal is more susceptible to infections.
Lymph nodes filter, store, and activate?
B and T cells
The Innate Immune System is _______-__________.
Physical barriers = 1st line of defense
Examples:
Skin
Mucous membranes
Saliva
Urine and tears
Stomach acids
Inflammatory phagocytes:
Neutrophils
Macrophages
Basophils
Eosinophils
Natural killer cells
Non-specific.
The Adaptive Immune system is ________. The _____-mediated response and the _______ response are apart of the adaptive immune system
Specific, cell, humoral
What makes up the cell-mediated response?
T-lymphocytes, including suppressor, helper, and cytotoxic T cells
The Humoral response is executed by?
B-lymphocytes, such as antibodies (Igs)
The innate immune response acts?
Rapidly
The adaptive immune response acts?
Slowly
What cells initiate the innate immune response?
Natural killer cells, professional phagocytes
What cells initiate adaptive immunity?
B-cells, T-cells
Chart for innate and adaptive immunity
Adaptive immune system is composed of specialized __________
cells and processes that __________ pathogens or prevent their _________.
systemic, eliminate, growth