Week 3 Flashcards
A 50 year old lifelong smoker presents with a persistent cough for 3 weeks with haemoptysis, and has noticed some weight loss. Diagnosis?
Lung cancer
Female 40 smoker presents with hoarse voice and stridor, and tiredness. Diagnosis?
Tumour in trachea compressing laryngeal nerve
What are some of the clinical findings of someone with lung cancer?
Finger clubbing Enlarged lymph glands Dull percussion Stridor Dysponea Thrombophlebitis (rare and red vein)
What is a pancoast tumour? Where does it effect?
Tumour of the pulmonary apex usually non-small cell cancers.
Can cause weakness and lack of control of the arm due to compression of brachial plexus
What are the common metastatic sites of lung cancer?
Liver, brain, bone, adrenal, skin
What are the four classifications of lung tumours?
Adenocarcinoma (glandular cancer)
Squamous carcinoma (keratin deposition)
Small cell carcinoma (worse type)
Large cell carcinoma (large cells no differntiation)
At what stage in development are the lungs made? What are they made from?
Week 5
Budded from oesophagus
When are the lung lobes and alveoli made during embryological development?
Week 6 for lobes
Week 8 for alveoli
What is the function of the conchae?
To cause turbulence of air allowing heating and moistening
What are the function of club cells in the bronchioles?
That detoxify and modulate immune and surfactant production
What is the function of type 2 alveolar cells? What is their cell description
To produce surfactant, they are polygonal shape with lamellar bodies that secrete surfactant
Women who is a non-smoker who presents with lung cancer. What is the most likely type she has?
Adenocarcinoma
During lung formation, what structure are they budded from? At what week?
Oesophagus week 5
At what week does the lung bud to make lobes and branches?
Week 6
What occurs in week 8 of embryological of lung development?
Alveoli
What is the treatment for small cell cancer?
Chemotherapy
What is the cell type in the oesophagus?
Squamous cell
What is the cell type in the stomach
Cuboidal
What is the difference between epidemic and pandemic?
Epidemic is due to antigenic drift (where the surface proteins slightly change) occuring in a set area
Pandemic is prevalent in a whole country or the world, occurring due to the complete changing of surface antigens
What is the treatment for small cell lung cancer?
Chemotherapy