Week 1 Flashcards
What two major muscles are involved with inspiration?
Diaphragm
External intercostal muscles
What is boyles law?
If volume of a gas increases the pressure of the gas decreases
A smaller alveoli is more likely to collapse than a larger one due to what law?
La places
What cell produced surfactant in the lung?
Type II alveolar cell/ Type II pneumocyte
What forces allow the alveoli to stay open?
Transmural pressure gradient
Pulmonary surfactnat
Alveolar interdependence
What is respiratory distress syndrome of the new born?
Where surfactant hasnt been produced yet due to baby being premature. So strain lungs as huge resistnace
Describe the step up treatments for asthma
SABA (salbutamol) as needed ICS (beclomethasone) + LABA ICS + LTRA (montelukast) LABA (salmeterol)/ ICS + LTRA (review) Increase ICS in above LAMA ( tiotropium) or methylxanthines (theophylline)
Define pulmonary ventilation
The volume of air breathed in and out per minute
Define alveolar ventilation
Volume exchanged between the atmosphere and alveoli per minute
Define daltons law
In a mixture of non-reacting gases the total pressure exerted is equal to the sum of the partial pressures of individual gases
What is the equation to determine the partial pressure of O2 in alveolar air when given the partial pressure of 02 in inspired air and co2 in arterial blood?
PA02= Pi02 - (PaC02/ 0.8)
Oxygen is more soluble across membranes than co2. True or false?
FALSE, co2 more soluble to make it easier to transfer Co2 into the lungs
The movement of gas across a tissue is proportional to the surface area and inversely proportional to its thickness. True or false?
True!
g= SA/ thickness
Define henrys law
If the partial pressure of a gas increases then the concentration of the diffused gas in the liquid would also increase proportionally
What are the two mechanisms of oxygen transportation
Bound to haemoglobin
Dissolved in plasma