Drugs For Asthma And Copd

Question 1

Corticoidsteroid
A. Function and side effects
B. Example through inhaled route
C. Example through oral route

Answer 1

A. Antiinflammatory. Causes immune suppression and imparied mucociliary clearance= pneumonia
B. Beclomethasone
C. Prednisolone

ENDS IN ‘ONE’= steroid

Question 2

Leukotriene receptor antagonist
A. Function
B. Example of stating route

Answer 2

A. Antiinflammatory targeting eosinophils (IL-5)

B. Oral route: montelukast

Question 3

Anti- IgE
A. Function
B. Example with route

Answer 3

A. Anti-inflammatory inhibiting the TH2 response that releases IgE
B. Injection of omalizumab

ENDS IN ‘LIZUMAB’ = anti something

Question 4

Anti-IL5
A. Function
B. Examples with route

Answer 4

A. Anti-inflammatory for asthmatics prevents the attraction of eosinophils which cause vasodilation etc.
B. Injection of mepolizumab or relizumab

IF ENDS IN ‘LIZUMAB’= anti something

Question 5

PDE4 inhibitors
A. Function
B. Route and example
C. What prescribed with?

Answer 5

A. preventing function of CAMP which promotes remodelling of airways in COPD. It is an anti-inflammatory
B. Roflumilast
C. LABA (beta-agonist) or LAMA (muscarinic antagonist)

Question 6

Beta agonist
A. Function
B. SABA/ LABA examples
C. With anything?

Answer 6

A. Bronchodilator- stimulate dilation of smooth muscle in airways
B. Saba- Salbutamol SS
Laba- salmeterol or formoterol
C. Can be with beclometasone (Steroid) in a combo inhaler

ENDS IN OL= beta agonist

Question 7

Muscarinic receptor
A. Function
B. Long acting example and short acting

Answer 7

A. Acetylcholine receptors that form g-protein complexes used as a bronchodilator
B. LAMA (antagonist)- tiotropium
SAMA (antagonist)- ipratropium

END IN TROPIUm= muscarinic

Question 8

Methylxanthines
A. Function
B. Examples of the oral route

Answer 8

A. Bronchodilator and anti-inflam, boosts CAMP
B. Theophylline- maintanence
Aminophylline- acute attacks

ENDS IN ‘phylline’= methylxanTHINES