Week 2: The Brainstem Flashcards
Why is the brainstem of significant importance?
- It carries almost all information between brain and rest of nervous system
- it is the location of many crucial nuclei (which holds cranial nerve function, consciousness, cerebellar circuits, muscle tone, posture, autonomic function and the list goes on…
- it hosts structures critical to basic survival
What are the 4 main components of the brainstem?
- Holds cranial nerve nuclei and related structures.
- Long tracts that contain descending motor pathways, ascending motor pathways and viscerosomatic pathways.
- Cerebellar circuitry
- Reticular formation
What are the 3 main regions of the brainstem?
Midbrain
pons
medulla
Another name for midbrain is:
mesencephalon
What are the 3 regions of the mesencephalon?
tectum
tegmentum
basis pedunculi
What two structures are located in the tectum?
superior colliculi
inferior colliculi
What is the orientation of the brain stem?
ventral or anterior
What is the orientation of this brain stem?
posterior or dorsal
What is the orientation of this brainstem?
lateral
Name this brainstem cross section:
Rostral midbrain
Name this brainstem cross section
Caudal Midbrain
Name this brainstem cross section
pontomesenphelic junction
Name this brainstem cross section:
Rostral Pons
Name this brainstem cross section:
caudal pons
Name this brainstem cross section:
Rostral Medulla
Name this brainstem cross section:
caudal medulla
What is special about white and grey matter on these myelin stained specimens?
the way white matter and grey matter are flip flopped. white matter is grey matter and grey matter is white matter.
What are the major associations associated with the mesencephalon?
vision hearing motor control sleep and wake cycle alertness temperature regulation
What cranial nerves are located externally on the midbrain or mesencephalon?
Cranial nerve 3 and 4
Is the superior colliculi located more rostral or caudal in the midbrain?
rostral
is the inferior colliculi located more caudal or rostral?
caudal
What are the 3 most basic layers of the midbrain?
Tectum
tegmentum
basis pedunculi
Name all of the structures located in the tegmentum (hint there are 9).
- multitude of ascending and descending tracts
- substantia nigra
- reticular formation
- ventral tegmental area
- red nuclei
- CN 3 oculomotor nuclei
- CN 4 trochlear nuclei
- Superior Cerebellar peduncles
- Raphe nuclei
Name all of the structures located in the tegmentum (hint there are 9).
- multitude of ascending and descending tracts
- substantia nigra
- reticular formation
- ventral tegmental area
- red nuclei
- CN 3 oculomotor nuclei
- CN 4 trochlear nuclei
- Superior Cerebellar peduncles
- Raphe nuclei
What are the 3 structures of the tegmentum that are only located in the cross section of the rostral midbrain?
ventral tegmental area
red nuclei
CN 3 oculomotor nuclei
What are the 3 structures that are only located in the cross section of the caudal midbrain?
CN 4 Trochlear nuclei
Superior cerebellar peduncles
Raphe nuclei
The Basis Pedunculi is a section of the midbrain that contains what structure?
Crus cerebri
The crus cerebri are:
large bundles of somatotopically organized axons containing fibers from motor pathways.
The cerebral peduncles consists of:
substantia nigra and the basis pedunculi
What cranial nerve emerges from the surface area of the pons?
CN 5 (trigeminal nerve)
The pons is associated with:
sleep
respiration
swallowing
bladder control
The pons is divided into 2 regions:
the basilar pons
pontine tegmentum
what 2 structures are located within the basilar pons?
deep pontine nuclei
descending motor pathways to spinal cord and cerebellum
There are a lot of structures in the pontine tegmentum but they can be broken down into 8 groups or larger structures. What are the 8 structures?
- reticular formation
- cranial nerve nuclei
- cerebellar peduncles
- deep cerebellar peduncles
- ascending sensory pathways
- descending motor pathways
- trapezoid body
- additional important nuclei
What are the cranial nerve nuclei associated with the pontine tegmentum?
CN 5 nuclei (trigeminal)
CN 6 nuclei (abducens)
CN 7 nuclei (facial)
CN 8 nuclei (vestibular)
Of the cranial nerve nuclei located in the pontine tegmentum. which ones are located in the CAUDAL pons?
trigeminal, abducens, facial and vestibular
Of the cranial nerve nuclei located in the pontine tegmentum. which ones are located in the ROSTRAL pons?
trigeminal and vestibular
What are the 3 cerebellar peduncles in the pontine tegmentum
superior, middle and inferior peduncles
Of the cerebellar peduncles located in the pontine tegmentum, which are located in the CAUDAL pons?
Superior, middle and inferior
Of the cerebellar peduncles located in the pontine tegmentum, which are located in the Rostral pons?
superior and middle
Are the deep cerebellar nuclei located caudally or rostrally?
caudal
is the trapezoid body located caudally or rostrally?
caudal
What are the names of the additional important nuclei located in the pontine tegmentum?
nucleus of Locus Ceruleus
Raphe Nucleus
superior olivary nucleus
Of the additional important nuclei in the pontine tegmentum, which of the nuclei are located rostrally?
nucleus of locus ceruleus
raphe nucleus
Of the additional important nuclei in the pontine tegmentum, which of the nuclei are located caudally?
superior olivary nucleus
The superior and middle cerebellar peduncles are located:
The caudal and rostral pontine tegmentum (or just the pontine tegmentum)
The inferior cerebellar peduncle is located only in the:
caudal pontine tegmentum
What cranial nerves emerge from the surface area of the medulla?
CN 6 - 12
Which part of the brain stem is considered to be the survival center?
medulla oblongata
What is the bridge between the brainstem and cerebellum?
cerebellar peduncles of the pontine tegmentum
At the trapezoid body, the fibers are in a decussation. This means that ______________ fibers cross.
auditory
why is it important to appreciate why fibers cross?
If there is a stroke above your caudal pons in your auditory pathway, the fibers have crossed from ear so there will be injury on the contralateral side. Below the caudal pons or the decussation, the impairment will be ipsilateral.
What is the medulla survival kit?
Heart Rate
Blood Pressure
Breathing
Swallowing
Why is the medulla called the survival center?
Because it is responsible for the function of your cardiovascular, respiratory and vasomotor centers.
It controls autonomic functions.
The Myelencephalon in the Medulla Oblongata is divided into:
Rostral and Caudal
What are the major 7 structures located in the Rostral Myelencephalon of the medulla oblongata?
- Reticular Formation
- Ascending tracts
- Medullary pyramids
- Inferior Cerebellar Peduncle
- Open Medulla
- Inferior olivary nuclei
- cranial nerve nuclei
The medullary pyramids of the rostral medulla oblongata carries the:
major descending motor tracts
What cranial nerve nuclei are included in the rostral portion of the medulla oblongata?
CN 8 Vestibular Nuclei
Nucleus Solitarius
Nucleus Ambiguous
Spinal Trigeminal Nucleus
What are the 8 major structures included in the caudal section of the myelencephalon of the medulla oblongata?
- Central canal
- Reticular Formation
- Ascending tracts
- Medullary pyramids
- Cranial nerve nuclei
- inferior olivary nuclei
- medial lemniscus decussation
- pyramidal decussation (Cervicomedullary junction)
The ascending tracts in the caudal myelencephalon of the medulla oblongata hold what important structures?
Nuclei Gracilis and Cuneatus
The medullary pyramids contains what important structure in the caudal myelencephalon?
Descending motor tracts
What cranial nerve nuclei are including in the myelencephalon?
CN 10 Vagus motor nuclei CN 12 Hypoglossal nuclei Nucleus solitarius Nucleus ambiguous CN 11 Spinal Accessory Nucleus
The reticular formation can best be compared to:
an on and off switch
What occurs if the Reticular Formation is damaged?
Coma or death
The reticular formation is an intricate system composed of:
loosely clustered neurons
The reticular formation extends through central core of:
medulla
pons
midbrain
The projections of the reticular formation can be found in the:
thalamus
cerebellum
spinal cord
optic
What are the functions of the reticular formation?
- General arousal and awareness
- Reticular Activating System (RAS)
- ——- synapses with all major ascending tracts
- ——- functions in arousal from sleep - motor awareness
- ——- medial and lateral reticulospinal tracts - autonomic regulation