Week 2: Nucleic Acid (S&F) Flashcards
1
Q
is a nucleotide a monomer or a polymer
A
a monomer:
- form energy rich compunds (ATP)
- incolved in chemical signalling
- structural components of enzyme-cofactors
- building blocks of DNA.
2
Q
what is the structure of a nucleotide?
A
- 5 carbone (pentose) sugar
- phosphate group
- nitrogenous bases (A,T/U,C,G)
3
Q
what is the 5 carbon (pentose) structure of a nucleotide?
A
** - 1’ carbon =** bound to nitrogenous base
** - 2’ carbon = ** gives sugar its name - depending on presence/absence of OH group (RNA –> ribose + OH; DNA –> deoxyribose - OH)
** - 3’ to 5’ = ** bound to phosphate groups and associated with directionality of DNA strand
4
Q
function of nucleic acid
A
- encode information for protein synthesis
- stores genetic material which can be transferred to future generations
- can be copied with high fidelity
5
Q
what is RNA
A
- robonucleic acid
- simple, single stranded molecule
- mRNA, rRNA, tRNA, mciroRNA
- all transcribed from DNA template
- ribose sugar rather than deoxyribose sugar.
6
Q
what is DNA?
A
- deoxyribonucleic acid
- template for creating RNA and DNA
- stores genetic infomation
- double stranded unbranched polymer - arranged in a double helix.
- covalent bonds between sugar and phospate group (backbone); hydrogen bonds between bases
- bases are hydrophobic and backbone is hydrophillic