Week 2, Drugs for Pain

Question 1

Pain due to damage to injury to tissues is what type of pain?

Answer 1

Nociceptive pain

Question 2

Pain due to damage to the nerves is what type of pain?

Answer 2

Neuropathic pain

Question 3

Burning, shooting, and numbing pain is what type of pain?

Answer 3

Neuropathic pain.

Question 4

Sharp, throbbing, and aching pain is what type of pain?

Answer 4

Nociceptive pain

Question 5

dull, throbbing, aching pain in the abdominal area is what kind of pain?

Answer 5

Visceral pain

Question 6

Sharp, throbbing pain in the bone, tendon, joints and ligaments is what type of pain?

Answer 6

Deep Somatic pain

Question 7

Sciatica and Carpal Tunnel would be examples of what kind of pain?

Answer 7

Neuropathic pain

Question 8

Substance P is the name of a what?

Answer 8

Neurotransmitter

Question 9

What is substance P thought to be responsible for?

Answer 9

Receiving the pain message, and sending it up the spinal column to the brain

Question 10

What neurotransmitter is thought to receive the pain signal?

Answer 10

Substance P

Question 11

Where does Substance P send the pain signal?

Answer 11

Up the spinal column to the brain

Question 12

A group of neurotransmitters that try to interrupt or modify pain information are called what?

Answer 12

Endogenous Opioids

Question 13

What do Endogenous Opioids try to do?

Answer 13

Interrupt or modify the transmission of pain.

Question 14

Endorphins, dynorphins, enkephalins
are examples of what?

Answer 14

Endogenous Opioids

Question 15

What is an example of an Endogenous Opioid?

Answer 15

-Endorphins
-Dynorphins
-Enkephalins

Question 16

Opioids are Morphine-like substances that are responsible for treating what?

Answer 16

Moderate to severe pain

Question 17

Opiates are naturally occurring opioids. Opioids are what?

Answer 17

naturally OR synthetic.

Question 18

Finish this sentance:

“All Opiates are Opioids…”

Answer 18

“…But not all opioids are opiates.

Question 19

What are the strictly naturally occurring opioids called?

Answer 19

Opiates

Question 20

What are examples of naturally occurring opioids?

Answer 20

-Morphine
-Codeine

Question 21

What are examples of synthetic opioids?

Answer 21

-Hydrocodone
-Oxycodone

Question 22

Morphine and Codeine are what type of Opioids?

Answer 22

Opiates; Naturally occurring.

Question 23

Hydrocodone and oxycodone are what type of opioids?

Answer 23

Synthetic opioids

Question 24

What are the 3 types of Receptors for opioids?

Answer 24

Mu, Kappa, and Delta

Question 25

For pain, which of the opioid receptors are the most important?

Answer 25

Mu and Kappa

Question 26

Opioid agonist drugs stimulate which opioid receptors?

Answer 26

Mu and Kappa

Question 27

Opioid Antagonist drugs block which opioid receptors?

Answer 27

Mu and Kappa

Question 28

Delta opioid receptors are more tied to what element of the pain experience?

Answer 28

The Emotional Affective experience

Question 29

What is the Mechanism of Action for an Opioid Agonist?

Answer 29

To bind with Mu and Kappa receptor sites

Question 30

What is the primary use for an Opioid Agonist?

Answer 30

Relieve moderate to severe pain

Question 31

What is an example of a prototype opioid agonist?

Answer 31

Morphine is a prototype opioid agonist.

Question 32

What is Percocet an example of in regard to receptor binding?

Answer 32

An Opioid Agonist

Question 33

respiratory depression, sedation, nausea, and vomiting are adverse effects of what receptor binding drug class?

Answer 33

Opioid Agonist

Question 34

What are some adverse effects of an Opioid Agonist, such as morphine?

Answer 34

-Respiratory depression -Sedation -Nausea -Vomiting

Question 35

What do opioid antagonists do?

Answer 35

Block opioid activity.

Question 36

What is an emergency opioid antagonist used to treat an opioid overdose?

Answer 36

Naloxone (Narcan)

Question 37

What does Naloxone (Narcan) reverse in a patient?

Answer 37

Respiratory depression; Overdose symptoms.

Question 38

What opioid antagonist drug is used to treat symptoms of opioid toxicity, addiction, and overdose?

Answer 38

Naloxone (Narcan)

Question 39

What action will mixed agonist-antagonists take towards an opioid receptor?

Answer 39

They will bounce in and bounce out.

Question 40

How do agonist-antagonist effects compare with strict opioid agonists?

Answer 40

Agonist-antagonist opioids will have a lesser pain-relieving response, but will also have less adverse effects, such as a lesser chance of addiction.

Question 41

Which type of opioid will have less pain-relieving effects, but simultaneously less adverse effects?

Answer 41

Agonist-Antagonist opioids

Question 42

What are 3 things that a nurse should monitor when a patient is using an Opioid agonist medication, like Morphine?

Answer 42

-Respiratory Status -Urine output to check for Retention -Bowel movements to check for constipation

Question 43

What kind of opioid analgesic would be used to treat mild to moderate pain, fever, and inflammation?

Answer 43

Non-opioid analgesic. Did I get ya' with that one?

Question 44

What type of analgesic would be used in Neuropathic pain?

Answer 44

An Adjuvant analgesic

Question 45

A patient is experiencing throbbing and pulsating pain localized in their head. The patient reports feelings of nausea and has recently vomited. What is the patient experiencing?

Answer 45

A Migraine headache.

Question 46

Triptans and Ergot Alkaloids are used for treatment of what?

Answer 46

Migraine headaches.