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Pharmacology > Week 2, Drugs for Pain > Flashcards

Week 2, Drugs for Pain Flashcards

1
Q

Pain due to damage to injury to tissues is what type of pain?

A

Nociceptive pain

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2
Q

Pain due to damage to the nerves is what type of pain?

A

Neuropathic pain

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3
Q

Burning, shooting, and numbing pain is what type of pain?

A

Neuropathic pain.

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4
Q

Sharp, throbbing, and aching pain is what type of pain?

A

Nociceptive pain

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5
Q

dull, throbbing, aching pain in the abdominal area is what kind of pain?

A

Visceral pain

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6
Q

Sharp, throbbing pain in the bone, tendon, joints and ligaments is what type of pain?

A

Deep Somatic pain

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7
Q

Sciatica and Carpal Tunnel would be examples of what kind of pain?

A

Neuropathic pain

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8
Q

Substance P is the name of a what?

A

Neurotransmitter

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9
Q

What is substance P thought to be responsible for?

A

Receiving the pain message, and sending it up the spinal column to the brain

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10
Q

What neurotransmitter is thought to receive the pain signal?

A

Substance P

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11
Q

Where does Substance P send the pain signal?

A

Up the spinal column to the brain

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12
Q

A group of neurotransmitters that try to interrupt or modify pain information are called what?

A

Endogenous Opioids

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13
Q

What do Endogenous Opioids try to do?

A

Interrupt or modify the transmission of pain.

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14
Q

Endorphins, dynorphins, enkephalins
are examples of what?

A

Endogenous Opioids

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15
Q

What is an example of an Endogenous Opioid?

A

-Endorphins
-Dynorphins
-Enkephalins

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16
Q

Opioids are Morphine-like substances that are responsible for treating what?

A

Moderate to severe pain

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17
Q

Opiates are naturally occurring opioids. Opioids are what?

A

naturally OR synthetic.

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18
Q

Finish this sentance:

“All Opiates are Opioids…”

A

“…But not all opioids are opiates.

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19
Q

What are the strictly naturally occurring opioids called?

A

Opiates

20
Q

What are examples of naturally occurring opioids?

A

-Morphine
-Codeine

21
Q

What are examples of synthetic opioids?

A

-Hydrocodone
-Oxycodone

22
Q

Morphine and Codeine are what type of Opioids?

A

Opiates; Naturally occurring.

23
Q

Hydrocodone and oxycodone are what type of opioids?

A

Synthetic opioids

24
Q

What are the 3 types of Receptors for opioids?

A

Mu, Kappa, and Delta

25
Q

For pain, which of the opioid receptors are the most important?

A

Mu and Kappa

26
Q

Opioid agonist drugs stimulate which opioid receptors?

A

Mu and Kappa

27
Q

Opioid Antagonist drugs block which opioid receptors?

A

Mu and Kappa

28
Q

Delta opioid receptors are more tied to what element of the pain experience?

A

The Emotional Affective experience

29
Q

What is the Mechanism of Action for an Opioid Agonist?

A

To bind with Mu and Kappa receptor sites

30
Q

What is the primary use for an Opioid Agonist?

A

Relieve moderate to severe pain

31
Q

What is an example of a prototype opioid agonist?

A

Morphine is a prototype opioid agonist.

32
Q

What is Percocet an example of in regard to receptor binding?

A

An Opioid Agonist

33
Q

respiratory depression, sedation, nausea, and vomiting are adverse effects of what receptor binding drug class?

A

Opioid Agonist

34
Q

What are some adverse effects of an Opioid Agonist, such as morphine?

A

-Respiratory depression
-Sedation
-Nausea
-Vomiting

35
Q

What do opioid antagonists do?

A

Block opioid activity.

36
Q

What is an emergency opioid antagonist used to treat an opioid overdose?

A

Naloxone (Narcan)

37
Q

What does Naloxone (Narcan) reverse in a patient?

A

Respiratory depression; Overdose symptoms.

38
Q

What opioid antagonist drug is used to treat symptoms of opioid toxicity, addiction, and overdose?

A

Naloxone (Narcan)

39
Q

What action will mixed agonist-antagonists take towards an opioid receptor?

A

They will bounce in and bounce out.

40
Q

How do agonist-antagonist effects compare with strict opioid agonists?

A

Agonist-antagonist opioids will have a lesser pain-relieving response, but will also have less adverse effects, such as a lesser chance of addiction.

41
Q

Which type of opioid will have less pain-relieving effects, but simultaneously less adverse effects?

A

Agonist-Antagonist opioids

42
Q

What are 3 things that a nurse should monitor when a patient is using an Opioid agonist medication, like Morphine?

A

-Respiratory Status
-Urine output to check for Retention
-Bowel movements to check for constipation

43
Q

What kind of opioid analgesic would be used to treat mild to moderate pain, fever, and inflammation?

A

Non-opioid analgesic.

Did I get ya’ with that one?

44
Q

What type of analgesic would be used in Neuropathic pain?

A

An Adjuvant analgesic

45
Q

A patient is experiencing throbbing and pulsating pain localized in their head. The patient reports feelings of nausea and has recently vomited. What is the patient experiencing?

A

A Migraine headache.

46
Q

Triptans and Ergot Alkaloids are used for treatment of what?

A

Migraine headaches.

Pharmacology (19 decks)

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