Week 1, Ch 5

Question 1

How medicine changes the body, and how people react to a drug is an example of what field of study?

Answer 1

Pharmacodynamics.

Question 2

What does the Therapeutic Index tell us?

Answer 2

How safe a drug is

Question 3

Differences in drug responses in a single patient is known as what?

Answer 3

The Dose-Response relationship

Question 4

What is the Dose-Response relationship?

Answer 4

The differences in drug responses in a single patient

Question 5

How is a Dose-Response relationship obtained?

Answer 5

By observing and measuring a patient’s responses at different levels of the drug.

Question 6

A high therapeutic effect at a low dose of a drug is known as a drugs what?

Answer 6

Potency

Question 7

A drugs Potency refers to its what?

Answer 7

Its high Therapeutic effect at a low dose

Question 8

What is a drugs efficacy?

Answer 8

The maximum response the drug can create.

Question 9

The maximum response that a drug can create is known as its what?

Answer 9

A drugs Efficacy

Question 10

Which is more “important” or a patient’s Therapeutic response:
-Drug Potency
-Drug Efficacy

Why?

Answer 10

Drug Efficacy, because high Efficacy means that the effect on the body is more positive

Question 11

In order for a drug to work in a body, it needs to interact with what? After interaction, where does this interaction land?

Answer 11

-Need to interact with a molecule or chemical
-After interacting, they land in a Receptor. Usually a Protein.

Question 12

Where are Receptors located?

Answer 12

In the Plasma Membrane

Question 13

There are two different types of Receptors. What are they?

Answer 13

Alphas and Betas

Question 14

What is an Agonist?

Answer 14

A drug that makes an action that is greater than, to similar to, a response to an action that already exists in the body

Question 15

What is the difference between an Agonist and an Antagonist?

Answer 15

-An Agonist works with something.
-An Antagonist works against something.

Question 16

A drug that is copying the body’s normal response, or enhancing the body’s normal response, is an example of what?

Answer 16

An Agonist

Question 17

Drugs that produce a weaker form of the body’s natural response are called what?

Answer 17

Partial-Agonist, or Agonist-Antagonist drugs

Question 18

Partial-Agonist, or Agonist-Antagonist drugs produce what in the body?

Answer 18

A weaker form of the body’s natural response

Question 19

In regard to receptors, an Agonist is an agent that does what?

Answer 19

Latches on to a receptor to “block” it.

Question 20

In regard to receptors, what agent is competing with an agonist for control of a receptor?

Answer 20

An Antagonist

Question 21

Reducing or totally eliminating the body’s natural response is the effect of what agent in regard to receptors?

Answer 21

An Agonist

Question 22

What does a Functional Antagonist do in regard to an Agonist?

Answer 22

Inhibits the Agonist, but not by competing for a receptor, but by changing the Pharmacokinetic factors.