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Infectious Disease > Week 2 > Flashcards

Week 2 Flashcards

1
Q

Vesicular herpesviruses (3)

A

HSV1
HSV2
VZV

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2
Q

Mono-causing herpesviruses (2)

A

EBV

CMV

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3
Q

HHV8 causes

A

Kaposi Sarcoma

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4
Q

Poxviruses (2)

A

Smallpox

Molluscum

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5
Q

Naked Single Stranded Linear DNA virus

A

Parvo

Think dog leash

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6
Q

Naked double stranded linear DNA virus

A

adenovirus

Think two adenoids

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7
Q

Naked double stranded circular DNA virus

A

pappilloma

Think cockring

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8
Q

How do single stranded negative sense RNA viruses replicate?

A

RNA dependent RNA pol (note: all are enveloped)

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9
Q

Single stranded negative sense RNA viruses

A

Paramyxoviruses:
Measles
Mumps

Measles and mumps are nonsense

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10
Q

Single stranded positive sense RNA enveloped viruses

A

Rubella

Rubella sounds like an old west hooker, who is SENSE-ual in her nightgown (envelope)

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11
Q

Single stranded positive sense naked RNA viruses (2)

A

Picornoviridae
Enteroviruses
Bad pico de gallo gives you diarrhea, and you’re naked, whatever

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12
Q

Enteroviruses (5)

A 
Enterovirus
Coxsackievirus
Echovirus
Poliovirus
Rhinovirus

PREE Cox (sorry, Amanda)

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13
Q

Parvo causes _____ in kids

A

Fifth (smacked up cheeks)

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14
Q

Parvo causes _________ in preggerfolk

A

Hydrops fetalis

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15
Q

Other bad sequelae of parvovirus (not slapped cheek, not hydrops)

A

Aplastic anemia

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16
Q

Anti influenza antivirals (4)

A

Amantadine
Rimantadine
Oseltamivir
Zanamivir

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17
Q

Anti-herps (4)

A

Acyclovir
Ganciclovir
Famciclovir
Foscarnet

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18
Q

Anti hepatitis agents (5)

A 
Adefovir
Entecavir
Lamivudine
Tenofovir
Interferon
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19
Q

oseltamivir and zanamivir moa

A

inhibits neuraminidase mediated release from cell

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20
Q

Anti herp drug moa

A

block DNA synthesis from viral DNA

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21
Q

Cyclovir resistance comes from (there were a bunch of questions on this bullshit on the formative) (2)

A

Changes in viral TK

Changes in DNA pol

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22
Q

Ganciclovir adverse effect

A

bone marrow suppression

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23
Q

Cidofivir adverse effects

A

nephrotoxicity and neutropenia

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24
Q

foscarnet adverse effect

A

nephrotoxic

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25
How long you gots to incubate blood cultures before you can call them negative
5 days
26
Enveloped DNA viruses
Herpes and Pox
27
Cell wall active ABX categories (5)
``` Beta-lactams Vancomycin Daptomycin Aztreonam Colistin ```
28
Beta-Lactam subgroups (3)
Penicillins Cephalosporins Carbapenems
29
Beta-lactamase inhibitors don't go _______
across the blood brain barrier
30
The only Beta-lactam that works for MRSA
Ceftaroline
31
IV Beta-lactam + BL-ase inhibitor
Ampicillin/Sulbactam
32
PO Beta-lactam + BL-ase inhibitor
Amoxicillin/Clavulanate
33
Beta lactam + BL-ase inhibitors cover (4)
GPC GNR Anaerobes Nasopharyngeal flora
34
Nasopharyngeal flora (3)
Strep pneumo H-flu Moraxella
35
If you want to cover pseudomonas with a PCN:
Piperacillin/Tazobactam
36
3 Penicillins
PCN Ampicillin Nafcillin
37
PCN covers (3)
Strep pyogenes / viridans / oral anaerobes
38
Ampicillin covers (2)
Enterococcus / nasopharyngeal flora
39
Nafcillin covers (2)
MSSA | Group A strep
40
1G cephalosporin (2)
Cefazolin / Cefalexin
41
1G cephalosporins cover (2)
Group A strep | Gram negative rods
42
3G cephalosporin
Ceftriaxone
43
Ceftriaxone can do this thing that other beta-lactams have trouble with
Cross the blood brain barrier
44
Ceftriaxone covers
Nasopharyngeal flora with Beta-lactamase
45
4G cephalosporin
Cefepime
46
Cefepime covers
pseudomonas
47
5G cephalosporin
Ceftaroline
48
Ceftaroline covers
MRSA
49
Carbapenems (2)
Imipenem and Meropenem
50
Carbapenems cover
Resistant gram negative rods
51
Vancomycin covers (2)
GPC and MRSA
52
When would you use vanco for a regular GPC?
Penicillin allergy
53
Vanco adverse effect
nephrotoxic
54
The "only" route you can use Vanco
IV (you can do PO for C diff, but young Henry Rollins was insistent that you can only give it IV: So only IV)
55
If you wanted to give Vanco, but someone has bad kidneys, you should use
Dapto
56
Dapto covers
Everything vanco covers, plus VRE
57
Dapto route
IV only
58
Dapto adverse effect
elevated CK
59
Gram negative rods, penicillin allergy:
aztreonam
60
Colistin covers
Gram negative rods
61
30s protein synthesis inhibitors (3)
Aminoglycosides Tigecycline Tetracyclines
62
Aminoglycosides (2)
Gentamycin | Amikacin
63
Aminoglycoside adverse effects (2)
ototoxic | nephrotoxic
64
Aminoglycosides cover (3)
``` GNR pseudomonas enterococcus endocarditis (with ampicillin or vanco) ```
65
Tetracyclines cover (5)
``` GAS MSSA some MRSA Intracellular GNR ```
66
Tetracycline adverse effects (3)
Teeth/bone | ototoxic
67
50s protein synthesis inhibitors (3)
Macrolides Clindamycin Linezolid
68
Macrolide
Azithromycin
69
Macrolides cover (4)
GAS MSSA Intracellulars Resistant Strep pneumo
70
Macrolide adverse effect
Qt prolongation
71
Qt prolongers (2)
Quinolones | Macrolides
72
Clindamycin covers (4)
GAS MSSA Some MRSA Oral anaerobes
73
If you want to use clindamycin for MRSA, you need this result on this test
Negative D test
74
Clindamycin adverse effect
diarrhea
75
Linezolid covers (3)
GPC MRSA VRE
76
Linezolid adverse effects (2)
Bone marrow suppression | Neuropathy
77
Nucleic acid synthesis inhibitors (2)
Sulfa/trimethoprim | Quinolones
78
Sulfa/trimethoprim covers (3)
MSSA MRSA (sulfatri is the "oral alternative") GNR (UTI)
79
Sulfa/trimethoprim does not cover
Group A strep
80
Sulfa/trimethoprim adverse effects (4)
bone marrow suppression rash interstitial nephritis SJS
81
Quinolones (2)
Moxifloxi | Ciprofloxacin
82
Moxifloxacin covers (2)
``` Nasopharyngeal flora (resistants) intracellulars ```
83
Ciprofloxacin covers
Gram negative rods

Infectious Disease (7 decks)

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