Week 12

Question 1

Tamoxifen

Answer 1

“comp inhibitor”of estrogen receptor - it prevents binding of estrogen to R

reduces cancer cell divs
must be taken regularly to act as TS

Question 2

herceptin

Answer 2

binds EGF-R (blocks EGF)

(antibody)

Question 3

driver mutations

Answer 3

most mutated TS and oncogenes

increase cell divs and number of cell mutations

Question 4

CT scan

Answer 4

computed tomography

xray

Question 5

b-cells

Answer 5

lymphocytes (wbcs) that secrete antibodies

Question 6

antibodies

Answer 6

infection fighters

• block proteins from binding receptors
• monoclonal

Question 7

hepatocytes

Answer 7

liver cells

Question 8

immortal cells

Answer 8

normal cells that have completely transformed into cancer cells

e.g. HeLa cells

Question 9

three antibodies that block GR Rs

Answer 9

herceptin, erbitux, perjeta

Question 10

lymphatic system

Answer 10

vessels and lymph nodes redistribute bodily fluids to prevent build up

but lymph vessels can help easy metastasis
nodes also = space for 2 tumour development

Question 11

leucocytes

Answer 11

wbcs in immune system (lymphatic)

Question 12

PET scan

Answer 12

a nuclear imaging test that uses a radioactive tracer to show how well organs and tissues are working