Week 11:Parkinson's Disease

Question 1

In Parkinson’s there is a ___ number of neurons in the substantial Nigeria that secrete ___, an ___ neurotransmitter. This leads to an imbalance between ___ and ___ in the basal

Answer 1

Decrease
Dopamine
Inhibitory
Excitation and inhibition

Question 2

In ____ Parkinson’s the cause is ______, and usually develops after the age of 60

Answer 2

Primary

Idiopathic

Question 3

In __ Parkinson’s the condition might be followed after _____, _____, or ___ disease. Other examples are a CNS infection, tumor, cerebral ischemia and anti-psychotic medication

Answer 3

Secondary
Encephalitis
Trauma
Vascular

Question 4

Early clinical manifestations of Parkinson’s

Answer 4

Fatigue 
Muscle weakness
 Muscle aches
Decreased flexibility 
Less spontaneous change in facial expression "mask like"

Question 5

Characteristic standing posture of Parkinson’s is ____, leaning ___ with the ___ and __ flexed

Answer 5

Stooped
Forward
Head
Neck

Question 6

Clinical manifestations are

Answer 6

Tremors at rest (unilateral then bilateral)
Rigidity
Bradykinesia 
Akinesia
Cogwheel ink

Question 7

CM of advanced disease

Answer 7

Dyshagia
Dementia
Slurred speech
Later in the disease- urinary retention, constipation, othostatic hypotension, uti, respiratory infections

Question 8

Dx Parkinson’s

Answer 8

No specific diagnostic test

CT or MRI to rule out brain tumors and neoplasms

Question 9

Management of Parkinson’s

Answer 9

Dopaminergics

Deep brain stimulation

Question 10

Nursing priority

Answer 10

Tertiary level of prevention strategies (safety)

Question 11

Parkinson’s is a ___ ______ disorder affecting ___ function though loss of ____ activity.

Answer 11

Progressive
Degenerative
Motor
Extra pyramidal