Week 10: Gastrointestinal Pathologies Part 2 Flashcards

1
Q

Crohn’s Disease

A
  • chronic inflammatory disorder of unknown cause most often in young adults
  • usually in terminal ileum of small bowel and/or proximal portion of the colon (Crohn’s colitis)
  • involves all layers of the GI tract
  • may have healthy and diseased areas interspersed
  • diffuse inflammation causes bowel loops to bind together
  • ulceration is common, as well as fistulas to bowel and other organs
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2
Q

Crohn’s Disease Radiographic Appearance

A
  • barium studies are done
  • irregular thickened and distorted mucosal folds
  • string sign = narrowed stretch of bowel with no mucosal pattern
  • skip lesion = diseased segments separated by healthy segments
  • transverse and longitudinal ulceration produces cobblestone appearance
  • CT also demonstrates thick mucosal walls
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2
Q

Small Bowel Obstruction

A
  • blockage of the small intestine
  • due to adhesions from previous surgeries, peritonitis, hernias, intussusception, volvulus, tumours or vascular insufficiency
  • may produce ischema with subsequent necrosis of bowel segment, sepsis and peritonitis
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3
Q

Adynamic (Paralytic) Ileus

A
  • fluid and gas (and any bowel contents) do not progress normally through a non-obstructed small (or large) bowel
  • can be post op, peritonitis, medication, trauma
  • part or all of small/large bowel fills to being peristalsis
  • localized ileus = small part of small or large bowel affected
  • colonic ileus = large bowel affected
  • treatment: NG tube, IV fluids
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3
Q

Inguinal Hernia Radiographic Appearance

A

protruding parts may be visible on imaging, not contained within abdominal cavity

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3
Q

Small Bowel Obstruction Radiographic Appearance

A
  • seen best on upright or decubitus abdomen
  • air fluid levels will be seen
  • loops of bowel will be distended/dilated proximal to the obstruction and collapsed distally
  • small bowl loops may distend so much they look like large bowel
  • may look like a step ladder or cascade
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4
Q

Localized Ileus

A
  • isolated distended loop (sentinel loop)
  • due to adjacent inflammatory process
  • radiographic appearance: one very distended loop
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5
Q

Colonic Ileus

A
  • excessive gaseous distention of bowel
  • often see massive distention of cecum
  • can look like mechanical obstruction (BE to rule out obstruction)
  • radiographic appearance: retention of large amounts of gas and fluid in dilated small and large bowel with no demonstrate point of obstruction
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5
Q

Inguinal Hernia

A
  • some of the abdominal contents, usually part of the small bowel, protrude through a weak are in the abdominal wall at the inguinal canals (one on either side of groin)
  • peritoneal sac bulges out too and surrounds the protruded contents
  • the hernia may persist outside or slide in and out of the abdomen
  • can cause constriction and/or ishcemia of protruding part
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6
Q

Intussusception

A
  • telescoping of one part of the intestinal tract into another because of peristalsis
  • can compromise the vascular supply = ischemic necrosis of the intussuscepted bowel
  • most common site in children: ileocecal valve
  • major cause of bowel obstruction in children
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7
Q

Intussusception Radiographic Appearance

A
  • xray: coiled spring appearance on contrast enema
  • CT: three concentric circles forming of soft tissue mass; target sign
  • us: donut shaped lesion
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8
Q

Hemangiomas - Benign Vascular Tumours

A
  • occur anywhere along the GI tract, most often in the small bowel, then large bowel and rectum
  • may cause bleeding
  • radiographic appearance: contrast displacing mass on contrast study
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9
Q

Diverticulum/Diverticulosis Radiographic Appearance

A
  • multiple round or oval outpouchings from bowel
  • thickened circular muscle may show sawtooth configuration
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10
Q

Diverticulum/Diverticulosis

A
  • diverticulum (single)/diverticula (plural) are out pouchings (herniations) of mucosa and submucosa through the muscular layers at points of weakness in the bowel wall
  • lack of fibre and water in the digestive track can lead to development
  • many diverticula = diverticulosis, may cause lower GI bleed
  • diverticula can occur in esophagus or duodenum
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10
Q

Polyps

A
  • benign neoplasms that project into the lumen of the bowel
  • mostly asymptomatic but certain types can become cancerous
  • colonoscopy can find and remove
  • found mostly in descending and sigmoid colon
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11
Q

Diverticulitis

A
  • complication of diverticular disease (diverticulosis), especially in the sigmoid region
  • retained fecal matter trapped in diverticulum can lead to inflammation and perforation
  • diverticulitis is inflammation of diverticula
  • may produce peri-diverticula abscess
  • may form fistula to adjacent organs
11
Q

Diverticulitis Radiographic Appearance

A
  • similar to diverticulosis, barium study demonstrates round or oval out pouching projecting beyond lumen (usually multiple)
  • contrast leaving from diverticula
  • abscess soft tissue mass
  • sawtooth configuration
  • can cause narrowing and rigidity of long section of colon with gradual transition to normal
12
Q

Polyps Radiographic Appearance

A
  • filling defect (barium enema)
  • bulge flat against wall if sessile polyp
  • stalk seen, polyp not flat against wall if pedunculated
12
Q

Sessile (Flat) Polyp

A
  • irregular lobulated surface
  • lie flat against colon wall
  • more likely to be malignant
  • inductive of cancer if over 2 cm in diameter, causes puckering/indentation/retraction at site or interval growth on subsequent exams
13
Q

Pedunculated Polyp

A
  • smooth surface with a long thin stalk
  • more likely to be benign
14
Q

Ulcerative Colitis

A
  • an inflammatory bowel disease, often begins in rectosigmoid area
  • may spread to involve entire colon, rarely involves small bowel
  • usually involves only the mucosal layer of the colon
  • alternating periods of remission and relapse
  • can become cancerous
  • symptoms: bloody diarrhea, abdominal pain, fever and weight loss
15
Q

Ulcerative Colitis Radiographic Appearance

A
  • plain radiographs of BE
  • granular mucosa
  • large nodular protrusions, mucosal thickening = thumbprint sign
  • deep mucosal ulceration = collar button appearance
  • loss of haustral markings from muscular atrophy and spasm = classic lead pipe appearance
16
Q

Toxic Megacolon

A
  • a complication of ulcerative colitis
  • extreme dilation of part or all of large colon
  • can lead to spontaneous bowel perforation
  • due to perforation risk, BE contraindicated
  • radiographic appearance: huge air filled colon
17
Q

Colorectal Cancer

A
  • cancer of the colon and rectum, usually in the rectum and sigmoid
  • peak age 50-70
  • needs early diagnosis for best outcome
  • several type
  • can cause polypoid mass or surround colon
  • ulceration common
  • may have multiple carcinomas or metachronous cancer
  • can metastasize
18
Q

Colorectal Cancer Radiographic Appearance

A

narrowed section of lumen with irregular contours, and rigid and tapered margins

19
Q

Annular Colorectal Carcinoma

A
  • annual lesions surround the bowel from outside
  • most common bowel cancer
  • starts from flat plaques of tumours (saddle lesions), easily missed of exams
  • usually in sigmoid
  • radiographic appearance: BE will demonstrate apple-core or napkin ring filling defect
20
Q

Large Bowel Obstruction

A
  • blockage of large bowel usually due to primary colon cancer
  • could be from diverticulitis or volvulus
  • less sever than small bowel obstruction
  • form more slowly with fewer fluid and electrolyte disturbances
  • causes increased pressure (closed loop) and risk of perforation, especially of cecum
21
Q

Large Bowel Obstruction Radiographic Appearance

A
  • if ileocecal valve working: dilated colon with thin walled distended cecum and little small bowel gas
  • if ileocecal valve not working: distended gas filled loops in small and large bowel
  • gas with abrupt stop seen on abdominal xray
  • CT recommended
22
Q

Volvulus Radiographic Appearance

A
  • BE can confirm
  • cecum volvulus: distended and displaced cecum in kidney shaped mass
  • sigmoid volvulus: distended rectum with lumen tapering towards volvulus area (bird’s beak sign)
22
Q

Volvulus

A
  • twisting of the bowel on itself that may lead to abdominal obstruction
  • most frequently involves the cecum and sigmoid colon
23
Q

Malrotation Of Bowel/Colon

A
  • twisting of the bowels, like volvulus bit occurs during fetal development
  • may be problematic or not, depending upon severity
  • volvulus symptoms may be first sign of malrotation: abdominal distention, pain, vomiting, constipation, bloody stools
  • radiographic appearance: abnormal location of bowel on image
24
Q

Imperforate Anus (Anal Atresia)

A
  • congenital lack of anal opening
  • often associated with a distended bowel
  • radiographic appearance: multiple dilated bowel loops filled with gas, absence of rectal gas