Week 1 Diabetes Mellitus Flashcards
Primary Effect Insulin
lower blood glucose levels by facilitating entry of glucose into peripheral tissues
Glucagon primary effect
Increase blood glucose to maintain normal levels and prevent hypoglycemia
Insulin stimulates
glucose uptake
conversion of glucose to glycogen
fatty acid and triglyceride production
Insulin inhibition
glucose breakdown
protein & fat breakdown
Glucagon stimulates
glycogen breakdown
glucose synthesis
fat breakdown
ketone production
Glucagon inhibits
glycogen synthesis
Type I DM
Progressive destruction of insulin secretion (young age)
Type II DM
Decreased sensitivity to circulating insulin (adult onset)
Diabetes S&S
Polyuria
Polydipsia
Fatigue
Blurred vision
Weight loss
Random blood glucose test
less than 200mg/dL
Fasting blood glucose test
126mg/dL
Hemoglobin A1C
4-6%
there are various types
they all have various time
Dx for type II DM
often undx until organ damage present
Peripheral neuropathy or claudication often presenting s/s
50% have HTN
annual foot, eye exam
Type I DM Dx
kidneys, pancreas
polyuria/polydipsia
Diabetic ketoacidosis
DM life expectancy
life expectancy is 7 to 10 years shorter for those with poorly controlled DM
DM acute complications
Diabetic ketoacidosis
Hyperglycemia
hypoglycemia
Is diabetic ketoacidosis a medical emergency?
yes, more common in type I
Hyperglycemia acute complications
> 300mg/dl blood glucose
glucose in urine
dehydration
more common in type II
Hypoglycemia acute complications
<70mg/dl blood glucose
activation of ANS
due to too much insulin, exercise, inadequate food
Hypoglycemia s&s
Rapid onset
Headache
Fatigue
Hunger
Tachycardia
Sweating
Anxiety
Confusion
Hyperglycemia s&s
Increased thirst
Frequent urination
Dry mouth
Nausea & vomiting
Shortness of breath
Hypoglycemia Observations
Rapid onset
Appears nervous irritable
Difficulty focusing
Pallor, sweating, Shaky
Increasing HR
What can PT do
sit pt down and give some kind of simple carb