Week 1 Diabetes Mellitus Flashcards
Primary Effect Insulin
lower blood glucose levels by facilitating entry of glucose into peripheral tissues
Glucagon primary effect
Increase blood glucose to maintain normal levels and prevent hypoglycemia
Insulin stimulates
glucose uptake
conversion of glucose to glycogen
fatty acid and triglyceride production
Insulin inhibition
glucose breakdown
protein & fat breakdown
Glucagon stimulates
glycogen breakdown
glucose synthesis
fat breakdown
ketone production
Glucagon inhibits
glycogen synthesis
Type I DM
Progressive destruction of insulin secretion (young age)
Type II DM
Decreased sensitivity to circulating insulin (adult onset)
Diabetes S&S
Polyuria
Polydipsia
Fatigue
Blurred vision
Weight loss
Random blood glucose test
less than 200mg/dL
Fasting blood glucose test
126mg/dL
Hemoglobin A1C
4-6%
there are various types
they all have various time
Dx for type II DM
often undx until organ damage present
Peripheral neuropathy or claudication often presenting s/s
50% have HTN
annual foot, eye exam
Type I DM Dx
kidneys, pancreas
polyuria/polydipsia
Diabetic ketoacidosis