Week 1 Blood Disorders

Question 1

a decrease in the number of erythrocytes, hemoglobin, or both

Answer 1

anemia

Question 2

decrease in the production of red blood cells

Answer 2

primary anemia

Question 3

increased destruction of red blood cells

Answer 3

secondary anemia

Question 4

bone marrow does not function properly or does not grow properly resulting in a lack of RBCs

Answer 4

aplastic anemia

Question 5

premature hemolysis of RBCs; causes heme to separate from RBC

Answer 5

hemolytic anemia

Question 6

insufficient amount of intrinsic factor to absorb B12

Answer 6

pernicious anemia

Question 7

hereditary and chronic disease characterized by crescent shaped RBCs

Answer 7

sickle cell anemia

Question 8

an idiopathic increase in the number of RBCs

Answer 8

erythrocytosis (polycythemia vera)

Question 9

sickle cell anemia is due to a single amino acid substitution (T/F)

Answer 9

true

Question 10

sickle cell anemia almost exclusively affects Caucasians (T/F)

Answer 10

false (African Americans, native Africans, & Mediterranean people)

Question 11

erythrocytosis decreases the viscosity of blood which decreases the chance for thrombi and clotting (T/F)

Answer 11

false (increases viscosity & chance for thrombi)

Question 12

erythrocytosis involves the bone marrow and is associated with increased amount of hemoglobin in the blood (T/F)

Answer 12

true

Question 13

increase in the number of white blood cells in the blood

Answer 13

leukocytosis

Question 14

leukocytosis is a reactive change to another condition (T/F)

Answer 14

true

Question 15

abnormal reduction in the number of white blood cells in the blood

Answer 15

leukopenia

Question 16

leukopenia is rarely associated with chemotherapy (T/F)

Answer 16

false (often associated)

Question 17

a malignancy of the hematopoietic tissues characterized by a massive increase (10 to 100x) in the number of white blood cells present in the body

Answer 17

leukemia

Question 18

disorder that involves formation of blood cells

Answer 18

hematopoietic disorder

Question 19

categories of leukemia (4)

Answer 19

Acute myelocytic (immature cells)
Acute lymphocytic (mature cells)
Chronic myelocytic (immature cells)
Chronic lymphocytic (mature cells)

Question 20

a hereditary bleeding disorder marked by a deficiency of blood-clotting proteins

Answer 20

hemophilia

Question 21

Type A hemophilia is due to ____

Answer 21

a lack of blood clotting protein factor VIII (8)

Question 22

Type B hemophilia is due to ____

Answer 22

a lack of blood clotting protein factor IX (9)

Question 23

Type __ hemophilia is also known as ____

Answer 23

B
Christmas disease

Question 24

Males transmit hemophilia, however, almost always, only females exhibit the disease complications (T/F)

Answer 24

false (females transmit, males exhibit disease)

Question 25

low platelet count

Answer 25

thrombocytopenia

Question 26

platelet count below 500 million results in platelets being less effective at forming clots (T/F)

Answer 26

false (less than 100 million)

Question 27

condition in which spontaneous bleeding occurs in the subcutaneous tissues, causing the appearance of purple patches on the skin

Answer 27

purpura

Question 28

purpura is extravascular and cannot be removed by embalming (T/F)

Answer 28

true