Week 1 Flashcards
What is Homeostasis?
The condition of equilibrium (balance) in the body’s internal environment.
A dynamic process by which we adjust to changes in the environment.
Is Homeostasis of one variable independent on another?
No- one variable depends on another
What is the regulated (sensed) variable
It had sensors (‘receptors’) within the system that’s send afferent signals to the brain to keep the regulated variable within a limited range
What is the feedback system for the arterial P02?
What is the feedback system for mean arterial pressure?
What is the feedback system for blood glucose concentration?
What is the feedback system for core body temperature?
What is the feedback system for core body temperature?
What is a tightly controlled variable and give an example?
A variable that at any given time is close to a predicted value
E.g partial pressure of oxygen in the blood, acid balance (PH), partial pressure or C02 in blood, blood pressure
What is a loosely controlled variable & give an example?
the variable may fluctuate in response to diurnal rhythms. E.g blood glucose, internal body temperature, body water & body weight
What is Set Point?
a physiological value that the body works to maintain
How is the regulated variable returned to normal?
Gain- when the variable is lowered and needs increasing
Reset- when the variable is increased and needs decreasing
What is the equation for a gain in the regulated variable?
What does a large gain indicate?
- more sensitive regulation
- maintains better normal conditions
What is negative feedback?
acts to reduce an effect and opposes the change
What is the most common regulatory feedback?
negative
Describe an example of negative feedback?
What is positive feedback?
Acts to increase an effect
describe an example of positive feedback
What is feedforward loop? and example?
physiological responses in anticipation of a change in a variable
E.g heart rate increasing prior to a running race
What is a reflex response?
involuntary response to a stimuli. It requires knowledge from an integrating centre and a circuit that connects the receptor and effector (hormones & transmitters)
what is a local response? & example?
a response that doesn’t involve nerves or hormones. Allows individual parts of the body to self regulate.
e.g autocrine and paracrine system
Describe the reflex arc loop?
What is Allostasis? & example?
involves both short and long term adaptations. E.g elevated heart rate during exercise
Is the human brain bigger than is should be?
Yes- typically the brain scales with body size but our brain is much bigger given our body size