Weed lecture part 2 Flashcards
Cannabis indica is mostly used in MEDICINAL CANNABIS :); used in oncology for cancer or chemo related pain it can also be used in HIV or AIDs patients to help decrease nausea and to increase appetite
____________: higher CBD content and lower THC
content
Users experience relaxing effects, which may
also…
- Provide pain relief
- Decrease nausea
- Increase appetite
Cannabis indica
Cannabinoids: ___________ phytochemicals
aromatic
Tetrahydrocannabinol (_______)
Primary psychoactive compound Cannabis sativa (High THC, Low CBD)
THC
Cannabidiol (_______)
Used for pain relief, movement disorders, anxiety, depression, and more
Cannabis indica (High CBD, Low THC)
CBD
Indica=in da couch
Sativa = Energetic high
_______ - Tetrahydrocannabinol
Primary psychoactive component
Secondary metabolite produced by the
cannabis plant to protect from…
Environmental stressors
Insect predation (stops insects from wanting to eat it
Ultraviolet light
THC
THC crosses the blood brain barrier so that’s why it has that psychoactive component :)
_________(Marinol)
Synthetic version of THC marketed as a CIII drug
Dronabinol
Dronabinol (Marinol)
Treatment of chemotherapy-induced nausea/vomiting
(CINV)
_________ stimulant in the treatment of anorexia
appetite
Dronabinol (Marinol)
Exerts complex CNS effects, appetite stimulation mediated via
interaction with ______________receptors in the hypothalamus
cannabinoid
Dronabinol (Marinol)
Contraindications:
Absolute - _________oil hypersensitivity
sesame oil
CBD - Cannabidiol
Treatment of ___________disorders (epilepsy)
___________disorders (anxiety, psychosis)
- Analgesia (used for pain relief)
neurological
psychiatric
Unlike THC, CBD is not psychoactive You will not get high from CBD
CBD was helpful in the creation of Epidiolex!!
Cannabidiol (Epidiolex)
Standardized cannabidiol extract
NOT a ______________drug (there’s only one active ingredient)
not a botanical drug
Cannabidiol (Epidiolex)
Developed from the “Charlotte’s Web” strain of cannabis
Very high CBD content, low THC
Epidiolex
Reduces neuronal ____________
excitability
Side effects of Epidiolex
Watch for _____________ - jaundice, vomiting
Contraindication with _________ allergy - flavoring
Sedation is common
hepatotoxicity
strawberry allergy
Two most well known cannabinoids are THC and CBD
___________ effect is the idea that all of the cannabinoids whether its CBD,THC,etc they all work together synergistically to create an enhanced therapeutic effect…the idea being that CBD alone might not be as effective as CBD,THC,CBN, all of them because they are all chemicals…all cannabinods and they all have their own interactions with each other which might effect by either agonizing or antagonizing metabolism of certain other cannabinoids within the body…extract might be more effective the whole is greater than the sum of its part
Entourage effect
From Prohibition to Legalization
Controlled Substances Act (CSA) of 1970
Marijuana becomes a __________ drug
Joined heroin and LSD as having “high potential for abuse
and no recognized medical use”
Schedule I
Medical Cannabis
Medical Use
Now legal in 48 States, DC, and 4 out of 5 territories
Recreational Use of Marijuana Still illegal federally